赖春晓 雷浩强

【摘要】 目的：对比消化道动脉灶性出血患者内镜下注射福爱乐组织胶、聚桂醇治疗的临床效果及安全性。方法：选取2017年3月-2018年12月于笔者所在医院治疗的80例消化道动脉灶性出血患者，按随机数字表法分为对照组（n=40）、治疗组（n=40），分别行内镜下注射聚桂醇、福爱乐组织胶治疗，观察两组止血效果、不良反应、治疗后住院时间等情况。结果：治疗组止血成功率高于对照组（P<0.05）;治疗组治疗后4个月内再出血率低于对照组，但差异无统计学意义（P>0.05）;治疗组治疗后平均住院时间显著短于对照组（P<0.05）;治疗组总有效率显著高于对照组，不良反应发生率显著低于对照组（P<0.05）。结论：内镜下注射福爱乐组织胶应用于消化道动脉灶性出血患者治疗中，可获得更理想止血效果，且安全性更高。

【关键词】 消化道动脉灶性出血 内镜 组织胶 聚桂醇 不良反应

doi：10.14033/j.cnki.cfmr.2019.29.010 文献标识码 B 文章编号 1674-6805（2019）29-00-03

[Abstract] Objective： To compare the clinical efficacy and safety of endoscopic injection of Fuaile tissue glue and Lauromacrogol in patients with gastrointestinal arterial focal hemorrhage. Method： Eighty patients with gastrointestinal arterial focal hemorrhage who entered the hospital from March 2017 to December 2018 were selected and divided into the control group （n=40） and the treatment group （n=40） according to the random number table. Endoscopic injection of Lauromacrogol and Fuaile tissue glue were performed respectively. The hemostatic effect， adverse reactions， length of hospital stay after treatment and so on were observed in the two groups. Result： The success rate of hemostasis in the treatment group was higher than that of the control group （P<0.05）. The rebleeding rate of the treatment group was lower than that of the control group within 4 months after treatment， but the difference was not statistically significant （P>0.05）. After treatment， the average length of hospital stay of the treatment group was significantly shorter than that of the control group （P<0.05）. The total effective rate of the treatment group was significantly higher than that of the control group， and the incidence of adverse reactions was significantly lower than that of the control group （P<0.05）. Conclusion： Endoscopic injection of Fuaile tissue glue for the treatment of patients with gastrointestinal arterial focal hemorrhage can achieve better hemostatic effect and higher safety.

[Key words] Gastrointestinal artery focal hemorrhage Endoscopy Tissue glue Lauromacrogol Adverse reaction

First-authors address： Zhongshan Huangpu Peoples Hospital， Zhongshan 528429， China

消化道動脉灶性出血具有出血量大、速度快、无法自发止血的特点，如患者未能及时获得有效救治，可在短时间内发生休克，甚至死亡[1]。目前，针对消化道动脉灶性出血治疗的方法较多，但各种方法应用过程中均存在优缺点，尚无集有效性、安全性为一体的理想的治疗方案[2]。研究显示，仅给予消化道动脉灶性出血患者药物止血治疗，较难获得理想止血效果，而内镜注射止血治疗可获得更高止血成功率[3]。本研究主要将内镜下注射福爱乐组织胶、聚桂醇两种方式应用于消化道动脉灶性出血患者中的临床治疗效果及安全性进行对比，做如下报告。

1 资料与方法

1.1 一般资料

选取笔者所在医院救治的消化道动脉灶性出血患者80例为研究对象。纳入标准：（1）因黑便或/和呕血入院治疗;（2）经相关临床检查明确诊断为消化道动脉灶性出血;（3）病历资料保持完整。……