陈涛

【摘 要】目的：探讨稳心颗粒联合胺碘酮在冠心病心律失常治疗中的临床应用效果。方法：选择2016年7月—2017年7月来我院进行治疗的86例冠心病心律失常患者作为此次研究对象，将其分成对照组与观察组，每组43例。对照组采用常规胺碘酮治疗方式，观察组在对照组常规胺碘酮治疗方式上给予稳心颗粒进行治疗，比较两组患者治疗效果。结果：观察组患者总有效（88.37%）显著高于对照组患者（72.09%），两组间比较具有统计学差异（P<0.05）。观察组患者不良反应发生率（9.32%）与对照组（11.62%）比较无明显差异（P>0.05）。结论：稳心颗粒联合胺碘酮在冠心病心律失常治疗中效果显著，可使治疗效果明显增高，且不良反应率低，值得临床推广应用。

【关键词】冠心病；心律失常；胺碘酮；稳心颗粒；联合治疗

abstract objective： to explore the clinical application effect of metacarpal granules combined with amiodarone in the treatment of arrhythmia of coronary heart disease. Methods： 86 patients with coronary heart disease arrhythmia who were treated in our hospital from July 2016 to July 2017 were selected as subjects of this study， and were divided into control group and observation group， with 43 patients in each group. The control group was treated with routine amiodarone treatment， and the observation group was treated with metacarpal granules on the routine amiodarone treatment of the control group， and the treatment effect of the two groups was compared. Results： the total efficacy of patients in the observation group （88.37%） was significantly higher than that in the control group （72.09%）， and there was a statistical difference between the two groups （P<0.05）. There was no significant difference （P>0.05） between the observation group and the control group （11.62%）. Conclusion： wenxin granule combined with amiodarone is effective in the treatment of cardiac arrhythmia of coronary heart disease， which can increase the treatment effect significantly， and the rate of adverse reactions is low， which is worthy of clinical application.

Keywords： coronary heart disease； Arrhythmia； Amiodarone； Metacentric particles； The combination therapy

【中圖分类号】R541 【文献标识码】A 【文章编号】1672-3783（2018）10-03--01

随着人们生活水平以及生活结构的不断 生情况及NYHA分级方面对比差异均无统计学意义 变化，冠心病的临床发病率呈逐年上升趋势，该病起 病急，对心脏功能影响大。冠心病是冠状动脉血管发生动脉粥样硬化病变而引起血管腔狭窄或阻塞，造成心肌缺血、缺氧或坏死从而引起一系列临床症状的心脏疾病，具有起病急、病情进展快等特点[1]。心律失常是心血管系统的常见疾病之一，一旦发生心律失常将致使病情急速恶化，严重威胁患者的生命[2-3]。本文主要探讨稳心颗粒联合胺碘酮在冠心病心律失常治疗中的临床应用效果，为冠心病患者创面有效控制心律失常提供合理的参考，详细报道如下。

1 一般资料与方法