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实时三维超声心动图对缺铁性贫血患者左心房容积与功能的研究

2018-12-14陈新颜顾晓薇

中国医学创新 2018年27期

陈新颜 顾晓薇

【摘要】 目的:應用实时三维超声心动图(RT-3DE)评价缺铁性贫血(IDA)患者左心房容积和功能的变化,探讨其临床应用价值。方法:60例IDA患者按照血红蛋白(Hb)浓度分为两组:A组

33例Hb>90 g/L、B组27例Hb<90 g/L。健康成年人作为C组30例。脉冲多普勒测量舒张期二尖瓣口前向血流舒张早期E峰及二尖瓣环侧壁峰值速度E′,计算E/E′值。应用RT-3DE测定左心室收缩末期左心房最大容积(LAVmax)、左心室舒张末期左心房最小容积(LAVmin)、左心房主动收缩前左心房容积(LAVpre),所有测值用体表面积(BSA)校正得出LAVImax、LAVImin、LAVIpre。计算心房主动射血分数(LAAEF)、被动射血分数(LAPEF)及左心房整体射血分数(LAEF),对比分析三组结果,并对上述参数与E/E′值进行相关性分析。结果:与C组比较,B组的LAVImax、LAVImin、LAVIpre、LAAEF均显著增大(P<0.05),LAPEF、LAEF均显著降低(P<0.05),A组除LAAEF和E/E′增大外其他项指标无明显变化。而患者E/E′值与LAVImax、LAVImin、LAVIpre呈显著性正相关(P<0.05),与LAAEF、LAPEF、LAEF呈显著性负相关(P<0.05)。结论:IDA患者常具有左心房结构与功能的改变,应用RT-3DE技术可进行有效的临床评估,并可间接反映左心室舒张功能状况。

【关键词】 实时三维超声心动图; 缺铁性贫血; 左心房容积与功能

Study on Left Atrial Volume and Function in Patients with Iron Deficiency Anemia by Real-time 3D Echocardiography/CHEN Xinyan,GU Xiaowei.//Medical Innovation of China,2018,15(27):0-022

【Abstract】 Objective:To evaluate the change of left atrial volume and function in patients with iron deficiency anemia(IDA) by real-time 3D echocardiography(RT-3DE).Method:A total of 60 patients with IDA were selected,according to the degree of hemoglobin(Hb) ther were divided into light-level anemia(group A,Hb>90 g/L) and middle-level anemia(group B,Hb 60-90 g/L).Another 30 healthy people were selscted as group C.The peak flow velocity of mitral valve(E) and left ventricular lateral wall mitral annulus(E′) were measured and E/E′ was calculated.The LAmaximum volume(LAVmax),LAminimum volume(LAVmin),LA volume pre contraction(LAVpre) were measured by RT-3DE,then adjusted by body surfsce area(LAVImax,LAVImin,LAVIpreA).Then LA total ejection(LAEF),LA passive ejection fraction(LAPEF),LA active ejection fraction(LAAEF) were calculated.Result:Compared with group C,LAVImax,LAVImin,LAVIpreA,LAAEF in group B were increased(P<0.05),while LAPEF,LAEF were reduced(P<0.05);LAAEF and

E/E′ in group A was incresed(P<0.05),the other indexes had no obvious differences(P>0.05).The LAVImax,LAVImin,LAVIpre had positive correlation with E/E′(P<0.05),LAAEF LAPEF,LAEF had negative correlation with E/E(P<0.05).Conclusion:LA function and structure are changed in IDA patients,RT-3DE can evaluate effectively patients with IDA,and indirectly reflect the change of left ventricular diastolic function.

【Key words】 Real-time 3D echocardiography; Iron deficiency anemia; Left atrial volume and function

First-authors address:Affiliated Hospital of Jiangnan University, Wuxi 214062,China

doi:10.3969/j.issn.1674-4985.2018.27.005

缺铁性贫血(iron deficiency anemia,IDA)可以是一种独立疾病或其他疾病的伴随症状,常因营养因素、机体慢性失血、消化系统手术后铁吸收障碍等因素导致,长期的慢性贫血可能引发心脏结构及功能的异常。早期由于血红蛋白降低,为满足机体的需求,心排出量增加。随着病情进展,心脏负荷的增加常导致左心室肥厚、心腔扩大以及功能减退,严重的贫血性心肌病或可继发心力衰竭[1]。目前利用二维超声对左心室重构的研究较多,而关注左心房容积与功能报道较少。……

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