D—二聚体值与CT肺动脉栓塞指数对肺动脉栓塞诊断的相关性研究
2018-12-13符建明陈辉
符建明 陈辉
【摘要】 目的:探讨D-二聚体值与CT肺动脉栓塞指数(PAOI)对肺动脉栓塞诊断的相关性研究。方法:回顾性分析50例肺动脉CTA阳性的肺动脉栓塞患者的影像资料,计算肺动脉栓塞指数,根据Mastora评分方法进行PAOI评分,将患者分为轻度(<30%)、中度(30%~50%)、重度(>50%),与相应D-二聚体值进行对比,分析两者对肺动脉栓塞的诊断及严重程度评估价值。结果:轻度肺动脉栓塞患者CT肺动脉栓塞指数低于中度患者、重度患者,中度肺动脉栓塞患者CT肺动脉栓塞指数低于重度患者,差异均有统计学意义(P<0.05)。轻度肺动脉栓塞患者D-二聚体值高于中度患者、重度患者,中度肺动脉栓塞患者D-二聚体值低于重度患者,但差异无统计学意义(P>0.05)。结论:D-二聚体值与肺动脉CTA对肺动脉栓塞的诊断均有价值,但CT肺动脉栓塞指数对评估临床症状严重程度有意义。
【关键词】 肺动脉栓塞; CT肺动脉栓塞指数; D-二聚体值; 计算机体层成像
doi:10.14033/j.cnki.cfmr.2018.24.018 文献标识码 B 文章编号 1674-6805(2018)24-00-02
Correlation of D-dimer and CT Pulmonary Arterial Infarction Index in the Diagnosis of Pulmonary Embolism/FU Jianming,CHEN Hui.//Chinese and Foreign Medical Research,2018,16(24):-40
【Abstract】 Objective:To investigate the correlation between D-dimer and pulmonary artery embolism index (PAOI) in the diagnosis of pulmonary embolism. Method:The imaging data of 50 patients with pulmonary artery CTA positive pulmonary embolism were retrospectively analyzed.Pulmonary artery embolization index was calculated. The PAOI score was scored according to the Massoura method.The patients were divided into mild (<30%) and moderate (30%-50%) patients,Severe (>50%),and the corresponding D-dimer values were compared to analyze the value of the diagnosis and severity of pulmonary embolism.Result:The pulmonary embolism index of patients with mild pulmonary embolism was lower than that of moderate and severe patients.The pulmonary artery embolism index of patients with moderate pulmonary embolism was lower than that of severe patients(P<0.05).Although the D-dimer values in patients with mild pulmonary embolism were higher than those in moderate patients and those in severe patients,the D-dimer values in patients with moderate pulmonary embolism were lower than those in severe patients,but there was no statistically significant difference(P>0.05).Conclusion:D-dimer and pulmonary arterial CTA are valuable in the diagnosis of pulmonary embolism,but CT pulmonary embolism index is of significance for assessing the severity of clinical symptoms.
【Key words】 Pulmonary embolism; CT pulmonary embolism index; D-dimer value; Computer tomography
First-authors address:Rudong County Peoples Hospital,Rudong 226400,China
隨着我国人们生活水平的提高及饮食结构的改变,PTE 近年来发病率逐年上升,临床表现多样,缺乏特异性,漏诊率、误诊率高,如若不及时治疗,死亡率高。在美国,致死性的肺栓塞每年发生率约为20万例[1],也是公认三大致死性心血管疾病之一。在我国近期的统计资料表明肺血栓栓塞症为死因的第四位。所以早期确诊,及时治疗能提高肺血栓栓塞症的治疗成功率,降低死亡率。本研究收集行肺动脉CTA及D-D检查的60例,回顾性分析肺动脉CTA和D-二聚体对肺动脉栓塞的诊断价值,并分析两者的相关性。
1 资料与方法
1.1 一般资料
收集笔者所在医院2014年1月-2017年6月在临床怀疑肺动脉栓塞的患者中行CTPA检查阳性和D-D检查的患者50例,年龄22~84岁,平均69岁,其中男24例,女26例,包括轻度患者22例,中度患者24例,重度患者4例,排除心肝肾功能不全者,碘过敏者及妊娠者。……
