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刘东汉教授辨治脾胃病柴胡用药规律浅析

2018-09-18吕洋超崔国宁刘喜平

中国民族民间医药·下半月 2018年4期

吕洋超 崔国宁 刘喜平

【摘 要】 目的:通过对刘东汉教授在脾胃病治疗中的门诊处方进行处方整理,分析柴胡的临证用药规律。方法:搜集刘东汉教授门诊处方,建立方剂数据库,依据中医传承辅助平台(V2.5)分析其用药规律。结果:柴胡是脾胃病治疗中用药频次很高的一味药;临床用量段从底到高依次为6 g,10 g,20 g,30 g,其中10 g为常规用量;柴胡最常见的配伍为当归、半夏、香附、甘草、黄芪、白芍等药。基于复杂系统熵聚类发现,柴胡的潜在高频配伍为当归、橘红、白芍、干姜等药。结论:柴胡是刘东汉教授治疗脾胃病时常用的一味药,不同的用量作用各异:6 g主要发挥其升阳之功,10 g主要发挥其疏肝解郁之功,20 g、30 g主要发挥其退热之功。

【关键词】 脾胃病;中医传承辅助平台;柴胡

【中图分类号】R249.2 【文献标志码】 A 【文章编号】1007-8517(2018)08-0062-03

Abstract:Objective To select the clinical prescriptions of professor Liu-donghan in the treatment of spleen and gastric diseases, analyzing drug using regular of the radix bupleuri. Methods To set the prescription databases through the selected prescription and then base on the TCM auxiliary platform to analysis the drug using regular. Results The radix bupleuri is the widely used in the treatment of spleen and gastric. The clinical usage period from the low to the high are6 g, 10 g,20 g,30, Among them, 10 g is the regular used; The common compatibility of the radix bupleuri are the angelica, the pinelia, the incense, the licorice, the radix astragali and the radix paeoniae .etc. based on the complex system entropy clustering, we found that the potential of the radix bupleuris high-frequency compatibility are the angelia, the orange, the radix paeniae alba and the rhizome zingiberis and so on. Conclusion The radix bupleuri is the commonly used medicine by Liu-donghan in the treatment of spleen and gastric, the different dosage may play different roles: the dosage 6g of the radix bupleuri may play the role of raise Yang; the 10g play the role of smooth liver-qi stagnation; the 20 g,30 g mainly play the role of bring down a fever.

Keywords:The Disease of Spleen and Gastric; The TCM Auxiliary Platform;Radix Bupleuri

2015年版中國药典规定柴胡为伞形科植物柴胡(Bupleurum Chinense BC.)或狭 叶柴胡(Bupleurumscorzonerifolium Willd.)的干燥根,性味微寒,味苦辛,归心包络、肝胆、三焦经[1]。其在《神农本草经》云“主阳气下陷、平肝胆,三焦,包络相火,头痛,眩晕,目昏诸疾,及夫人热如血室,经水不调,小儿逗疹余热,五疳羸热”,其有和解退热、疏肝解郁、升阳举陷之功,是目前临床应用较多的一味药物。柴胡属植物的化学成分十分复杂, 迄今为止已报道含有柴胡皂苷、挥发油、黄酮、甾醇、多糖等多种成分。皂苷是柴胡属植物中的主要化学成分,也是发挥药效的重要部分[2]。现代药理研究发现其具有解热镇静,镇咳,抗细菌,抗炎保肝,治疗妇科疾病,促进酶分泌,调节免疫等作用[3]。……

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