依达拉奉联合舒血宁注射液治疗急性脑梗死的效果
2018-07-13杨丽
杨丽
[摘要] 目的 观察分析依达拉奉联合舒血宁注射液治疗急性脑梗死的临床效果。 方法 选择2013年1月~2016年2月北京市昌平区中医医院收治的急性脑梗死患者77例,按照就诊顺序随机分为治疗组(n=39)和对照组(n=38)。对照组患者在常规治疗基础上给予舒血宁注射液治疗,治疗组患者在常规治疗基础上给予依达拉奉联合舒血宁注射液治疗。观察并比较两组患者治疗前后的神经功能缺损程度和临床治疗效果。 结果 治疗组的神经功能缺损程度评分、日常生活活动自理能力评分及治疗有效率均明显优于对照组,差异有统计学意义(P < 0.05)。治疗后对照组血浆黏度及全血黏度较治疗前明显降低,差异有统计学意义(P < 0.05);治疗组治疗前后血浆黏度及全血黏度无明显变化(P > 0.05)。两组均未出现不良反应。 结论 舒血宁注射液联合依达拉奉治疗急性脑梗死效果显著,能有效改善患者神经功能及生活自理能力。
[关键词] 舒血宁;依达拉奉;急性脑梗死;疗效
[中图分类号] R743.33 [文献标识码] A [文章编号] 1673-7210(2018)04(b)-0074-04
[Abstract] Objective To observe the clinical efficacy of Edaravone combined with Shuxuening Injection in treatment of Acute Cerebral Infarction. Methods From January 2013 to February 2016, seventy-seven patients with acute ischemic stroke treated in Changping District Hospital of Traditional Chinese Medicine were selected, according to their visit sequences, they were randomly divided into treatment group (n=39) and control group (n=38). Patients in the control group were treated with Shuxuening Injection on the basis of regular treatment, and patients in the treatment group were treated with Edaravone combined with Shuxuening Injection. The neurologic impairment and effects after treatment were observed and compared. Results The defectiveness ratings of nervous functions, the assessment of self-care ability, and the efficacy of the treatment group were noticeably higher than those of control group, the differences were statistically significant (P < 0.05). Compared with before treatment, the plasma viscosity and total blood viscosity of the control group decreased significantly after treatment, and the difference was statistically significant (P < 0.05). There was no significant change in plasma viscosity and total blood viscosity in treatment group before and after treatment (P > 0.05). There was no adverse effect in both groups. Conclusion Shuxuening Injection combined with Edaravone has a significant clinical effect in treating acute cerebral infarction, which can effectively improve nervous function of the patients and their self-care ability.
[Key words] Shuxuening; Edaravone; Acute Cerebral Infarction; Efficacy
脑梗死也稱为缺血性脑卒中,是指由于脑部血液供应障碍、缺氧、缺血等原因引起的局限性脑组织缺血性坏死或脑软化[1]。急性脑梗死占缺血性脑卒中的80%[2]。该病发病急骤、病死率高,若不及时治疗患者预后状况不佳且会出现严重的并发症,给患者及家庭带来沉重的负担。因此,探寻及时有效的方法治疗急性脑梗死具有重要的实际意义。北京市昌平区中医医院(以下简称“我院”)采用依达拉奉联合舒血宁治疗急性脑梗死取得了满意的临床效果,现报道如下:
1 资料与方法
1.1 一般资料
选择2013年1月~2016年2月我院收治的77例急性脑梗死患者为观察对象,按照患者就诊顺序,采用随机数字表法将其分为两组,治疗组39例,男21例,女18例;……
