陈士建

[摘要] 目的 研究分析在SLE（系统性红斑狼疮）患者诊断中采用NA抗体检验和血清体液免疫检验的诊断效果。方法 研究样本方便选自该院2016年1月—2017年1月收治的80例进行SLE检验受检者，按照受检者患病与否将其分为对照组与观察组，对照组受检者为健康受检者，观察组受检者为SLE患者，对比两组受检者血清体液免疫检验中的IgG、IgA、IgM、C3、C4等指标及NA抗体检验中的抗ds-DNA抗体、抗Sm抗体、抗SSB抗体等指標。结果 ①观察组患者IgG指标为（22.44±3.27）g/L、IgA为（2.96±0.55）g/L、IgM为（1.97±0.62）g/L、C3为（0.63±0.20）g/L、C4为（0.14±0.03）g/L；对照组患者IgG指标为（10.36±2.60）g/L、IgA为（1.83±0.37）g/L、IgM为（1.53±0.40）g/L、C3为（1.34±0.25）g/L、C4为（0.28±0.05）g/L，两组受检者血清指标检测水平差异有统计学意义（P<0.05）。②观察组受检者与对照组受检者NA抗体检验中的阳性率比较具有显著差异，其中观察组受检者阳性率为90.0%，高于对照组受检者0.0%（P<0.05）。 结论 在SLE（系统性红斑狼疮）患者诊断中采用NA抗体检验和血清体液免疫检验具有显著效果。

[关键词] 胃癌；早期诊断；血清胃蛋白酶原；胃镜；诊断效果

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2018）02（a）-0174-03

Clinical Value of NA Antibody Test and Serum Humoral Immunoassay in the Diagnosis of SLE

CHEN Shi-jian

Laboratory Department， Laiwu Central Hospital， Laiwu Steel Group， Laiwu， Shandong Province， 266071 China

[Abstract] Objective This paper tries to study the diagnostic effect of NA antibody test and serum humoral immunoassay in the diagnosis of SLE （systemic lupus erythematosus） patients. Methods The study samples were Convenient selected from this hospital from January 2016 to January 2017 of 80 cases of SLE test subjects. According to the subjects illness or not， it was divided into control group and observation group. In the control group， the subjects were healthy subjects， and the observation group was SLE patients. The serum humoral immunity test of two groups IgG， IgA， IgM， C3， C4 and other indicators and NA antibody test anti-dsDNA antibody， anti-Sm antibody， anti-SSB antibody and other indicators were compared. Results ①In the observation group， the IgG was（22.44±3.27）g/L， the IgA was（2.96±0.55）g/L， the IgM was （1.97±0.62）g/L and the C3 was （0.63±0.20）g /L， C4 was（0.14±0.03）g/L； and those in the control group were the index of IgG was （10.36±2.60）g/L，IgA was （1.83±0.37）g/L，IgM was （1.53±0.40）g/L and C3 was （1.34±0.25）g/L， and C4 （0.28±0.05）g/L， respectively. There was significant difference between the two groups in serum test（P<0.05）. ②There was significant difference in the positive rate of NA antibody between the subjects in the observation group and the control group， in which the positive rate was 90.0% in the observation group and 0.0% in the control group（P<0.05）. Conclusion The use of NA antibody test and serum humoral immunoassay in SLE （systemic lupus erythematosus） patients have a significant effect.

[Key words] Gastric cancer； Early diagnosis； Serum pepsinogen； Gastroscopy； Diagnostic effect

SLE（系统性红斑狼疮）属于一种免疫性疾病，在目前临床诊疗中仍旧无典型病理因素[1]。根据多年来诊疗经验分析，SLE疾病的发病因素包括免疫因素、内分泌因素、遗传因素、环境因素等综合性因素[2]。患者发病后血清免疫球蛋白与补体水平均有不同程度的异常，因此常应用NA抗体检验和血清体液免疫检验进行临床诊断，该次研究对该院2016年1月—2017年1月收治的40例SLE患者与40例健康受检者采用NA抗体检验和血清体液免疫检验，探究其应用价值，现报道如下。

1 资料与方法

1.1 一般资料

研究样本：该院80例SLE患者与健康受检者。诊断标准：所有患者均经该院临床病理诊断并参照《国际红斑狼疮诊断标准》[3]确诊。分组方式：按照患者患病与否将其分为对照组（40例）与观察组（40例），对照组患者为SLE患者，观察组为健康受检者。……