高阳

[摘要] 目的 研究埃索美拉唑與铝碳酸镁联合治疗胃溃疡合并胃出血的临床疗效，并对患者的胃出血复发率进行探讨。方法 方便选取该院2014年5月—2015年5月期间所收治的152例胃溃疡合并胃出血患者作为该次研究对象，按照就诊时间对患者进行分组治疗，研究组和对照组各76例，对照组应用埃索美拉唑治疗，研究组患者则在对照组的治疗基础上加用铝碳酸镁治疗，对比分析两组患者的治愈率、总有效率以及胃出血的复发率。结果 研究组治愈62例，治愈率为81.58%，对照组治愈32例，治愈率为42.11%，研究组治愈率明显高于对照组，且研究组患者的总有效率（97.37%）（74/76）明显高于对照组（73.68%）（56/76）；研究组胃出血复发率为2.63%（2/76），对照组复发率为18.42%（14/76），研究组患者的胃出血复发率明显低于对照组，两组之间差异有统计学意义（P<0.05）。结论 埃索美拉唑与铝碳酸镁联合治疗胃溃疡合并胃出血的临床效果明显，能够有效提高患者的治愈率与临床总有效率，且疾病复发率小，值得临床进一步应用。

[关键词] 埃索美拉唑；铝碳酸镁；胃溃疡；胃出血

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2018）02（a）-0100-03

Clinical Analysis of Esomeprazole Combined with Aluminum Magnesium Carbonate in the Treatment of Gastric Ulcer Complicated with Gastric Hemorrhage

GAO Yang

Department of Gastroenterology， Infectious Diseases Hospital of Heze， Heze， Shandong Province， 274000 China

[Abstract] Objective This paper tries to study the clinical efficacy of esomeprazole combined with magnesium aluminum carbonate in the treatment of gastric ulcer complicated with gastric hemorrhage， and to explore the recurrence rate of gastric bleeding in patients. Methods 152 patients with gastric ulcer complicated with gastric hemorrhage from May 2014 to May 2015 were convenient selected as the objects of this study， according to the time of treatment， they were divided into two groups， the study group and the control group， each of 76 cases， the control group was treated with esomeprazole. The patients in the study group were treated with aluminum magnesium carbonate on the basis of the control group. The cure rate， the total effective rate and the recurrence rate of gastric hemorrhage were analyzed. Results The study group cured 62 cases， the cure rate was 81.58%， the control group cured 32 cases， the cure rate was 42.11%， the study group was significantly higher than the control group， and the study group of the total effective rate was （97.37%） （74/76 ）， significantly higher than that of the control group （73.68%） （56/76）. The recurrence rate of gastric bleeding was 2.63% （2/76） in the study group and 18.42% （14/76） in the control group. The recurrence rate was significantly lower than the control group， the difference between the two groups was statistically significant （P<0.05）. Conclusion The clinical effect of esomeprazole combined with aluminum magnesium carbonate in the treatment of gastric ulcer with gastric hemorrhage is obvious， which can effectively improve the cure rate and clinical effective rate of the patients， and the recurrence rate of disease is small and deserves further clinical application.

[Key words] Esomeprazole； Aluminum magnesium carbonate； Gastric ulcer； Gastric bleeding

随着人民生活水平的不断提高，食品与安全问题成为了当前国民患病率持续增高的主要危险因素，据相关学者调查研究[1]，我国患有胃溃疡以及胃出血的患者正在呈现逐年上升的趋势，患者患病的主要临床表现为食欲低下，体质低下，给患者的生活与学习带来了很大程度的不便[2-3]，基于此，该文就对胃溃疡合并胃出血治疗临床治疗方案进行探讨，针对该院在2014年5月—2015年5月期间所收治的152例胃溃疡合并胃出血患者作为病例进行分析，并研究埃索美拉唑与铝碳酸镁联合治疗的效果，现报道如下。……