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不同胰岛素治疗妊娠糖尿病的有效性及安全性观察

2018-06-04税惠群

健康必读·下旬刊 2018年4期
关键词:安全性有效性

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【摘 要】目的:探讨不同胰岛素治疗妊娠糖尿病的有效性与安全性。方法:随机选取2015年2月至2018年1月期间我院收治的60例妊娠糖尿病患者的临床资料进行统计学分析,将其按照患者入院顺序分为常规组和治疗组,每组30例,常规组给予常规胰岛素进行皮下注射,治疗组给予诺和锐胰岛素进行治疗,比较两组患者治疗前空腹、早餐后2h、治疗后空腹、早餐后2h血糖量值,治疗总有效率,并发症发生率。结果:治疗前两组患者血糖值差异对比无统计学意义(P>0.05);治疗后,两组患者血糖值均显著改善,治疗组血糖值显著优于常规组,数据对比具有统计学意义(P<0.05);治疗组治疗总有效率(93.33%)显著优于常规组(83.33%),两组数据对比具有统计学意义(P<0.05);治疗组并发症发生率(10.00%)低于常规组(20.00%),数据差异对比具有统计学意义(P<0.05)。结论:相比较常规胰岛素治疗糖尿病,诺和锐胰岛素注射治疗可降低并发症发生率,提高治疗总有效率,治疗效果更显著。

【关键词】不同胰岛素;妊娠糖尿病;有效性;安全性

Abstract Objective:To explore the efficacy and safety of different insulin in the treatment of gestational diabetes.Methods: statistical analysis were randomly selected from February 2015 to January 2018 in our hospital 60 cases of gestational diabetes in patients with clinical data, the patients were randomly divided into routine group and treatment group, 30 cases in each group, the conventional group received routine insulin subcutaneous injection, the treatment group was given insulin aspart treatment, were compared between the two groups fasting, after breakfast, 2h after treatment, fasting blood glucose after breakfast 2H value, the total efficiency of treatment and complications.Results: before treatment, two groups of patients with blood glucose difference was not statistically significant (P>0.05); after treatment, two groups of patients with blood glucose values were significantly improved in treatment group, blood glucose was significantly better than the conventional group, with statistically significant data comparison (P<0.05); the total efficiency of the treatment group (93.33%) was significantly higher than that of the conventional group (83.33%), the two groups have statistical significance comparing the data (P<0.05); the incidence of complications in the treatment group (10%) is lower than the conventional group (20%), statistically significant differences between data (P<0.05). Conclusion: compared to conventional insulin therapy for diabetes,Insulin aspart injection therapy can reduce the incidence of complications, improve the total efficiency of treatment,insulin aspart treatment effect is more significant.

Key words: Different insulin; gestational diabetes; efficacy; safety

【中圖分类号】 R749.053【文献标识码】 B 【文章编号】 1672-3783(2018)04-03-036-01

妊娠糖尿病是指妊娠前糖代谢正常或者存在潜在糖耐量减退的现象,导致其妊娠期出现糖尿病。据可靠数据显示,在糖尿病孕妇中,妊娠糖尿病占80%,对母儿的生命健康具有一定的安全威胁[1]。胰岛素是胰脏内的胰岛β细胞受内源性、外源性(葡萄糖、核糖、胰高血糖素等)的刺激而分泌的一种蛋白质激素,可以有效促进糖原、蛋白质、脂肪等的合成等。有效的胰岛素治疗可提高治疗有效率与安全性,但是不同的胰岛素治疗妊娠糖尿病患者会有不同的疗效。本文作者为探讨不同胰岛素治疗妊娠糖尿病的有效性与安全性,随机选取2015年2月至2018年1月期间我院收治的60例妊娠糖尿病患者的临床资料进行统计学分析,结果如下。

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