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30岁以下急性ST段抬高型心肌梗死患者临床特点分析

2018-04-20翟公伟赵培华滑艳

医学信息 2018年5期
关键词:危险因素

翟公伟 赵培华 滑艳

摘   要:目的  探討30岁以下急性ST段抬高型心肌梗死患者的临床特点。方法  选择首次发病的STEMI患者51例,按年龄分青年组17例(年龄18~30岁),对照组34例(年龄≥31岁),对两组人群常见的危险因素、临床特点、冠状动脉病变特点以及发病30 d内主要不良心血管事件发生率进行对比分析。结果  ①青年组中男性、吸烟、合并高血压、合并高脂血症患者比例明显高于对照组,差异有统计学意义(P<0.05);青年组体质量指数、左心室射血分数以及血清总胆固醇、甘油三酯、低密度脂蛋白胆固醇水平明显高于对照组,总胆红素水平低于对照组,差异有统计学意义(P<0.05);②青年组“罪犯血管”病变类型以单支病变、A型病变为主,对照组多为三支病变、分叉病变、C型病变,差异有统计学意义(P<0.05);③青年组发病30 d内梗死后心绞痛、心力衰竭、恶性心律失常的发生率明显低于对照组,差异有统计学意义(P<0.05)。结论  男性、吸烟、合并高血压、合并高脂血症是30岁以下STEMI患者突出的危险因素,其冠脉病变多为单支、A型病变,发病30 d内临床预后良好。

关键词:青年;心肌梗死;危险因素;冠脉造影

中图分类号:R542.22                                 文献标识码:A                               DOI:10.3969/j.issn.1006-1959.2018.05.026

文章编号:1006-1959(2018)05-0081-03

Clinical Characteristics of Acute ST-segment Elevation Myocardial Infarction under 30 Years of Age

ZHAI Gong-wei,ZHAO Pei-hua,HUA Yan

(Department of CCU,Jinghai District Hospital,Tianjin 301600,China)

Abstract:Objective  To investigate the clinical characteristics of acute ST segment elevation myocardial infarction(AMI)patients under 30 years of age.Methods  51 STEMI patients with first onset were divided by age youth group of 17 cases(age 18~30),the control group of 34 cases(aged≥31 years),risk factors,two groups of common clinical features,characteristics of coronary artery lesions and within 30 d of onset of major adverse cardiovascular events incidence were compared analysis.Results  ①The youth group in male,smoking,hypertension,and hyperlipidemia patients were significantly higher than the control group,the difference was statistically significant(P<0.05);youth group,body mass index,left ventricular ejection fraction,serum total cholesterol,triglyceride,low density lipoprotein cholesterol levels were significantly higher than the control group,the total bilirubin level compared with the control group, the difference was statistically significant(P<0.05).②In the young group,the types of"criminals blood vessels"were mainly single vessel lesion and A type lesion.The control group had three branches,bifurcation lesions and C lesions.The difference was statistically significant(P<0.05).③The incidence of angina pectoris, heart failure and malignant arrhythmia in the young group was significantly lower than that in the control group within 30 d after onset,and the difference was statistically significant(P<0.05).Conclusion  Men, smoking,hypertension and hyperlipidemia are prominent risk factors for STEMI patients under 30 years old.Their coronary lesions are mostly single and A lesions,and the prognosis is good within 30 d.

Key words:Young people;Myocardial infarction;Risk factors;Coronary angiography

目前,我国急性心肌梗死发病率呈逐渐上升,且有年轻化趋势[1]。既往流行病学研究表明,青年人群中,心肌梗死及症状性冠状动脉疾病发病率为3%[2]。目前,临床研究多集中于中老年患者急性心肌梗死防治,对30岁及以下急性心肌梗死的报道较少。本文旨在通过病例对照研究,分析30岁及以下急性ST段抬高型心肌梗死(ST-segment elevation myocardial infarction STEMI)患者的临床特点,报告如下。

1资料与方法

1.1一般资料  收集2010年1月~2016年12月于我院CCU科住院治疗,首次发病确诊为STEMI患者51例,均符合2015年《急性ST段抬高型心肌梗死诊断和治疗指南》的诊断标准。按年龄分青年组17例(18~30岁);对照组34例,年龄≥30岁。

1.2临床资料收集  临床指标:性别、年龄、吸烟史、体质量指数、高血压、糖尿病、高脂血症、早发心血管疾病家族史、心肌梗死部位、发病30 d内主要心血管事件。生化指标:甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖、总胆红素(TBIL)。冠脉造影观察指标:①根据冠……

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