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弥散加权成像在肝脏肿瘤性病变诊断中的临床价值

2018-03-29李红双

中外医疗 2018年2期

李红双

[摘要] 目的 探討和研究磁共振弥散加权成像在肝脏肿瘤性病变诊断中的应用价值。 方法 根据随机原则要求从2016年2月—2017年2月期间来该院就诊的肝脏良性肿瘤性病变患者中随机选取45例作为对照组研究对象,采取同样的方法从同时间段来该院就诊的肝脏恶性肿瘤性病变患者中选取45例作为试验组研究对象,入组患者均有明确的病理结果,比较两组患者磁共振弥散加权成像结果差异。结果 研究数据显示,肝细胞癌低b值、中b值、高b值分别为(2.48±0.46)、(1.54±0.50)、(1.15±0.33),转移瘤低b值、中b值、高b值分别为(2.74±0.66)、(1.73±0.55)、(1.37±0.28),脓肿低b值、中b值、高b值分别为(2.88±0.73)、(2.02±0.73)、(1.66±0.60),肝血管瘤低b值、中b值、高b值分别为(3.44±1.03)、(2.34±0.69)、(1.53±0.50),在表观扩散系数 (ADC) 值的低b值和中b值2个阶段,局灶性结节增生与转移瘤、肝脓肿间,血管瘤和其他病变间,肝癌细胞和肝脓肿间的扩散系数比较差异有统计学意义(P<0.05);在表观扩散系数 (ADC) 值的高b值阶段,血管瘤和肝细胞癌、局灶性结节增生间、局灶性结节增生与转移瘤、肝内胆管细胞癌间的扩散系数比较差异有统计学意义(P<0.05)。结论 肝脏肿瘤性病变采取磁共振弥散加权成像检查并分析ADC值,有助于提高磁共振对肝脏肿瘤良恶性判断的准确性,值得临床推广。

[关键词] 肝脏肿瘤;磁共振弥散加权成像;表观扩散系数

[中图分类号] R445 [文献标识码] A [文章编号] 1674-0742(2018)01(b)-0181-03

[Abstract] Objective To study and research the application value of diffusion-weighted imaging in diagnosis of liver tumor lesion. Methods 45 cases of patients with benign liver tumor lesions diagnosed in our hospital from February 2016 to February 2017 were randomly selected as the control group, while 45 cases of patients with malignant liver tumor lesions diagnosed in our hospital in the same way at the same period were selected as the test group, and all admission patients had clear pathological results, and the differences in the diffusion-weighted imaging results were compared between the two groups. Results The research data showed that the hepatocellular carcinoma low b value, moderate b value, high b value were respectively (2.48±0.46),(1.54±0.50),(1.15±0.33), and the metastatic tumor low b value, moderate b vale, high b value were respectively (2.74±0.66),(1.73±0.55),(1.37±0.28), abscess low b value, moderate b value, high b value were respectively (2.88±0.73),(2.02±0.73),(1.66±0.60), and the hepatic hemangioma low b value, moderate b value and high b value were respectively (3.44±1.03),(2.34±0.69),(1.53±0.50), and in the ADC values of the low b value and moderate b value, the differences between focal nodular hyperplasia and metastatic tumor, hepatapostema, angioma and other lesions, hepatoma carcinoma cell and hepatapostema were statistically significant(P<0.05), and in the ADC values of high b value, the differences between the angioma and hepatocellular carcinoma, focal nodular hyperplasia, focal nodular hyperplasia and metastatic tumor and intrahepatic cholangiocellular carcinoma were statistically significant(P<0.05). Conclusion The diffusion-weighted imaging in diagnosis of liver tumor lesion for examining and analyzing the ADC value contributes to improving the accuracy of magnetic resonance in determining the malignant and benign liver tumors, which is worth clinical promotion.

[Key words] Liver tumor; Diffusion-weighted imaging; ADC

磁共振弥散加权成像(DWI)借助组织中水分子弥散运动的特点进行成像,伴随组织病理变化其图像信号强度也会随之改变[1]。以往磁共振弥散加权成像在超急性期脑梗死中应用较为广泛,其无辐射、分辨率高、无创伤、多角度和多参数成像的优点得到广大医务工作者的普遍认可,但是在腹部的应用报道临床较为少[2]。肝脏肿瘤在我国具有较高的发病率,包括良性病变和恶性病变两组类型,类型不同决定其治疗措施也不同,因此提高肝脏肿瘤性病变诊断的及时性和准确性意义重大,以往主要通过影像学检查方法如磁共振、螺旋CT等进行诊断和观察[3]。……

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