肺结核合并糖尿病患者营养状态的影响因素分析
2018-03-21刘阳
刘阳
[摘要] 目的 探讨影响肺结核(PTB)合并糖尿病(DM)患者营养状态不良的危险因素。 方法 回顾性分析我院60例PTB-DM患者临床资料,根据治疗后6个月患者的营养状态将其分为营养状态良好组(n=37)和营养状态不良组(n=23)。将两组临床资料做统计学分析处理,利用多因素Logistic回归分析法分析影响PTB-DM患者预后营养状态不良的高危因素。 结果 两组性别和出院后吸烟情况比较差异无统计学意义(P>0.05);经多因素Logistic回归分析发现,年龄、入院时出现病灶空洞情况、出院后饮酒与DM控制情况均为影响PTB-DM患者预后营养状态不良的独立危险因素(P<0.05)。 结论 年龄较大、入院时存在病灶空洞、出院后存在饮酒和DM控制较差情况均与PTB-DM患者预后营养状态不良关系密切,需引起重视。
[关键词] 肺结核;糖尿病;营养状况;危险因素
[中图分类号] R587.1 [文献标识码] A [文章编号] 1673-9701(2018)02-0020-03
[Abstract] Objective To explore the risk factors of malnutrition in the patients with pulmonary tuberculosis (PTB) complicated with diabetes mellitus (DM). Methods The clinical data of 60 patients with PTB-DM in our hospital were retrospectively analyzed. According to the nutritional status of patients after 6 months of treatment, they were divided into favorable nutrition group(n=37) and malnutrition group (n=23). The clinical data of the two groups were analyzed statistically. Multivariate Logistic regression analysis was used to analyze the risk factors of malnutrition prognosis in PTB-DM patients. Results There was no statistically significant difference in gender and smoking after discharge between the two groups(P>0.05); multivariate Logistic regression analysis showed that age, incidence of cavitary lesion upon admission and drinking and DM control after discharge were all dependent risk factors of malnutrition prognosis in PTB-DM patients(P<0.05). Conclusion Advanced age, cavitary lesion upon admission, drinking and poor DM control after discharge are closely related to the malnutrition prognosis in PTB-DM patients, and great attention should be drawn to them.
[Key words] Pulmonary tuberculosis; Diabetes mellitus; Nutritional status; Risk factors
我国糖尿病(DM)与肺结核(PTB)发病率均较高,而DM的病理生理学特征使患者身体素质降低而增加PTB发生风险,也影响PTB患者的治疗效果,故PTB-DM患者的预后状态受到学术界广泛关注[1]。PTB-DM患者治疗后机体调节功能尚未完全恢复,常使患者营养状态处于较差水平,严重影响患者的预后状态,也增加疾病复发风险。基于此,本研究对PTB-DM患者临床资料进行回顧性分析,试图发现影响PTB-DM患者营养状态不良的危险因素,现报道如下。
1 资料与方法
1.1 一般资料
回顾性分析2015年1月~2016年2月在我院治疗的60例PTB-DM患者的临床资料,且所有患者进行6个月病情随访,评估其治疗6个月后的营养状态。纳入标准:符合2008年版《中国结核病防治规划实施工作指南》[2]中结核病诊断标准和1999年世界卫生组织颁布的DM诊断标准[3];年龄>18岁者;出院时……
