APP下载

脾脏转移性绒毛膜癌伴脾破裂1例报道并文献复习

2018-02-07代景友雷明露李三石

中外医学研究 2018年2期

代景友+雷明露+李三石

【摘要】 目的:探讨脾脏转移性绒毛膜癌伴脾破裂出血的臨床特点、诊断及治疗。方法:分析笔者所在医院近期对1例脾脏转移性绒毛膜癌伴破裂出血患者的诊治情况,并复习相关文献。结果:术中发现患者脾脏下极有一包块且破裂出血,术后病理诊断脾脏绒毛膜癌,血β-hCG 121 475 IU/L。胸部CT示两肺转移瘤。结论:临床上脾脏转移性绒毛膜癌伴破裂出血在脾破裂中极为少见,对于脾脏占位,尤其是处于生育年龄的女性患者,应注意该病的鉴别诊断。

【关键词】 绒毛膜癌; 脾脏转移性绒毛膜癌; 脾破裂

doi:10.14033/j.cnki.cfmr.2018.2.095 文献标识码 B 文章编号 1674-6805(2018)02-0186-03

【Abstract】 Objective:To investigate the clinical manifestation,disagnosis and treatment of metastatic choriocarcinoma with rupture of spleen.Method:Aanalyzing the process of therapy for the patient diagnosed with metastatic choriocarcinoma with rupture of spleen,and reviewing the related literature.Result:We found a tumor with rupture and bleeding in the bottom of spleen during operation,postoperative pathological reported choriocarcinoma of spleen,the β-hCG was elevated at 121 475 IU/L,and the chest CT reported multimetastatic carcinomas of lungs.Conclusion:Metastatic choriocarcinoma with rupture of spleen in splenic rupture is rare inclinical medicine,and it shall be paid attention to the differential diagnosis of splenic tumors,especially for the female patients of child-bearing age.

【Key words】 Choriocarcinoma; Metastatic choriocarcinoma of spleen; Splenic rupture

First-authors address:Bozhou Peoples Hospital,Bozhou 236800,China

绒毛膜癌是一种多发生于育龄期女性的滋养细胞肿瘤,其特点是恶性程度高,易发生远处转移。绒毛膜癌的主要转移方式是血行转移,其转移部位以肺脏、阴道及脑多见[1-3],而脾脏转移仅占7%。滋养细胞的生长特点是破坏血管,致使各转移部位常发生局部出血。临床上脾脏转移性绒毛膜癌伴破裂出血在脾破裂出血中极为少见[4-5],这也增加了本病的诊断难度。因此,本文通过报道亳州市人民医院普外二科收治的1例脾脏转移性绒毛膜癌伴破裂出血患者的诊治过程,并结合近年相关文献,进一步阐述本病在临床中的诊断思维及治疗方案。

1 病例介绍

1.1 一般资料

患者,女,27岁。因“左上腹疼痛20 d,加重1 d”入院。患者于20 d前因左上腹疼痛就诊于浙江某医院,行腹部CT检查示:脾周积血,腹盆腔内较多积液。腹部增强CT示左中腹积血,增强后造影剂渗出,肠系膜血管破裂?……

登录APP查看全文