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慢性萎缩性胃炎伴胃癌前病变辨治思路

2018-02-01张强黄明河

中国中医药信息杂志 2018年2期

张强+黄明河

摘要:慢性萎缩性胃炎伴胃癌前病变是消化科疑难病证,其病程迁延日久,难以治愈。本文通过对病因、病机及病理的分析,认为其发病主要机理为脾胃虚弱、气滞血瘀、瘀毒蕴结,治宜健脾养胃、理气化瘀、解毒散结。

关键词:慢性萎缩性胃炎;胃癌前病变;健脾养胃;理气化瘀;解毒散结

DOI:10.3969/j.issn.1005-5304.2018.02.027

中图分類号:R259.733.2 文献标识码:A 文章编号:1005-5304(2018)02-0118-03

Ideas of Syndrome Differentiation in Treatment of Chronic Atrophic Gastritis with Precancerous Lesions

ZHANG Qiang, HUANG Ming-he

Shenzhen Hospital Affiliated to Guangzhou University of Chinese Medicine, Shenzhen 518033, China

Abstract: Chronic atrophic gastritis with gastric precancerous lesions is a kind of difficult disease of digestive disease, with long course of disease and difficulty in cure. This article believed that the main pathogenesis was spleen-stomach deficiency, qi-blood stasis and blood stasis poison accumulation by analyzing the causes, pathogenesis and pathology, which should be treated by nourishing spleen and stomach, regulating qi and blood circulation, detoxifying and dissipating stasis.

Keywords: chronic atrophic gastritis; gastric precancerous lesions; nourishing spleen and stomach; regulating qi and blood circulation; detoxifying and dissipating stasis

慢性萎缩性胃炎(chronic atrophic gastritis,CAG)是以胃黏膜腺体减少为主要特点的常见消化系统疾病,其中伴有肠上皮化生(IM)与异型增生(ATP)属胃癌前病变,与胃癌的发生关系密切。故阻断逆转CAG及IM、ATP的进展,是治疗CAG及防止胃癌发生的重要措施。笔者结合多年临床经验,针对本病的病因、病机、病理,从健脾养胃、理气化瘀、解毒散结探讨CAG伴IM、ATP的诊治。

1 脾胃虚弱、运化失常乃基本病机

因CAG常见脘腹痞满,故可归于“胃痞”范畴。CAG多由慢性浅表性胃炎(CSG)久病不愈,反复发作所致。若长期饮食不节、饥饱失常、劳倦内伤、喜怒忧思,均会伤及脾胃,使脾胃气机亏虚而出现运化失常。脾主运化,胃主受纳腐熟,脾升胃降,共同完成饮食之消化、吸收、输布,为气血生化之源、后天之本。慢性胃炎患者因长期致病因素影响,往往出现脾胃气虚甚至阳虚或胃阴亏虚。《张氏医通·诸气门》谓本病多为“脾胃虚弱、转运不及”。《丹溪心法·痞》又认为本病乃“脾气不和,中央痞塞,皆土邪之所为也”。CAG患者最常见症状是脘腹痞满、食少纳呆、少气懒言、倦怠消瘦或面色萎黄、大便溏薄、舌淡苔白、脉细弱,表明脾胃气虚是本病最重要的病机。……

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