张成雷　陈康寿　陈敏

【摘要】 目的：探討腹腔镜完整结肠系膜切除术治疗结肠癌的临床效果。方法：选取2014年

2月-2016年2月本院收治的结肠癌患者104例，按照随机数字表法将其分成观察组和对照组，每组52例。对照组采用开腹完整结肠系膜切除术治疗，观察组采用腹腔镜下完整肠系膜切除术治疗，比较两组患者手术过程中的持续时间、出血量、术后肛门排气时间、住院天数及并发症发生情况等。对两组患者均随访1年，观察两组患者的肿瘤复发率。结果：观察组与对照组手术时间比较，差异无统计学意义（P=0.076）；观察组术中出血量、术后排气时间与住院天数均少于对照组，比较差异均有统计学意义（P<0.05），观察组并发症发生率3.85%（2/52）低于对照组，差异有统计学意义（字2 =7.121，P=0.008）；术后对两组患者均进行1年随访，观察组复发率为1.92%（1/52），对照组复发率为15.38%（8/52），观察组肿瘤复发率显著低于对照组，差异有统计学意义（字2=5.960，P=0.015）。结论：采用腹腔镜下完整结肠系膜切除术治疗结肠癌效果显著，具有手术时间短、术中出血量少、住院时间、并发症发生率低等优点，且术后1年内肿瘤复发率也较低，具有重要的临床推广价值。

【关键词】 腹腔镜； 完整肠系膜切除术； 结肠癌

【Abstract】 Objective：To investigate the clinical effect of laparoscopic total mesorectal excision in the treatment of colon cancer.Method：From February 2014 to February 2016，104 colon cancer patients treated in our hospital were selected as the research objects，they were divided into observation group and control group according to random number table method，52 cases in each group.Control group was given open complete mesocolic excision treatment，and observation group with complete mesenteric laparoscopic resection，observed and compared the operation time，surgery bleeding volume，postoperative anal exhaust time，hospitalization time and complications occurrence rate of two groups.Two groups were followed up for 1 year，the recurrence rate of two groups were observed.Result：The operation time of two groups were no significant difference（P=0.076）；surgery bleeding volume，postoperative anal exhaust time，hospitalization time of observation group were less than those of control group，the differences were statistically significant（P<0.05）；complications occurrence rate of observation group was 3.85%（2/52），lower than that of control group，the different was statistically significant（字2 =7.121，P=0.008）.The two groups of patients were followed up for a period of 1 year，the recurrence rate of observation group was 1.92%（1/52），lower than that of control group 15.38%（8/52），the difference was statistically significant（字2=5.960，P=0.015）.Conclusion：Laparoscopic complete mesocolic resection in the treatment of colon cancer has significant effect，has a shorter operative time，less bleeding， hospitalization time，low complication occurrence rate，and postoperative 1 year recurrence rate is low，has important clinical value.

【Key words】 Laparoscopy； Complete mesenteric resection； Colon cancer

First-authors address：Zhanjiang Central Peoples Hospital，Zhanjiang 524000，China

doi：10.3969/j.issn.1674-4985.2017.25.032endprint

近年来，随着生活节奏的加快，人们饮食结构和作息规律也越来越不合理，致使结肠癌的发病率呈逐年上升的趋势，对患者的生活质量及生命造成严重威胁[1-4]。目前，临床上主要采用手术方法治疗结肠癌，随着医疗水平的提高，微创技术也得到不断发展，越来越受到患者的好评[5]。为了探讨腹腔镜完整结肠系膜切除术治疗结肠癌的临床效果，本院选取在2014年2月-2016年2月收治的104例结肠癌患者为研究对象，分别采用开腹完整结肠系膜切除术和腹腔镜下完整肠系膜切除术，效果显著，现报道如下。

1 资料与方法

1.1 一般资料 选取在2014年2月-2016年2月本院收治的结肠癌患者104例，所选患者均进行全面检查而确诊，并经本院伦理委员会批准，签署患者知情同意书。……