黎鹏?李晓燕?刘燕琼

[摘要] 目的 探析改良翼状胬肉切除与传统翼状胬肉切除术的临床观察。方法 临床选择2015年7月～2016年3月本院收治的初发性翼状胬肉患者80例（80只眼），根据随机数字表法分为对照组和观察组，每组40例（40只眼），观察组进行自体结膜瓣角膜缘干细胞移植术与小切口翼状胬肉切除联合疗法，对照组进行自体结膜瓣缘干细胞移植术与常规翼状胬肉切除术联合疗法，比较两组的恢复时间、手术时间、出血量、切口大小；比较两组的复发情况、患者的不适感、并发症等情况。 结果 观察组的恢复时间、手术时间、切口大小、出血量等临床指标显著优于对照组，差异有统计学意义（P<0.05）；观察组的不适感、复发情况、并发症情况显著低于对照组，差异有统计学意义（P<0.05）。 结论 初发性翼状胬肉应用改良翼状胬肉切除法不适感轻，恢复迅速，出血量少，手术时间短，临床效果确切，值得临床推广。

[关键词] 自体结膜瓣角膜缘干细胞；翼状胬肉；改良翼状胬肉切除术

[中图分类号] R779.6 [文献标识码] A [文章编号] 2095-0616（2017）14-188-04

Clinical effect observation of improved pterygium resection and conventional pterygium resection

LI Peng LI Xiaoyan LIU Yanqiong

Department of Ophthalmology，Xinyi People's Hospital，Xinxi 525300，China

[Abstract] Objective To compare the clinical effect of improved pterygium resection and conventional pterygium resection. Methods 80 patients with incipient pterygium （80 eyes） cured in our hospital from July 2015 to March 2016 were selected.They were randomly divided into two groups，40cases（40eyes） each group.Patients in observation group were treated with the combined therapy of conjunctival limbal stem cell autografting and minimal pterygium resection，and patients in control group were treated with the combined therapy of conjunctival limbal stem cell autografting and conventional pterygium resection.The patient's recovery time，operation time，bleeding amount，incision size as well as recurrence rate，discomforts and complications for two groups were compared. Results The clinical index of recovery time， operation time，incision size and bleeding amount of observation group were significantly better than those of control group（P<0.05）.The discomfort rate，recurrence rate and incidence rate of complications of observation group were significantly lower than those of control group（P<0.05）. Conclusion The improved pterygium resection has an obvious effect in patients with incipient pterygium.It can reduce the discomfort rate，promote the patient's recovery，decrease the bleeding amount，and shorten the operation time.It is worthy of clinical promotion.

[Key words] Conjunctival limbal stem cell autografting；Pterygium；Improved pterygium resection

翼狀胬肉是指结膜下和睑裂部出现组织增生、肥厚、变性，进一步向角膜内进展，如翼状，呈三角形，可能与烟雾、日光、风尘等长期慢性刺激密切相关，高发人群多为户外工作者[1]。翼状胬肉较小者有异物感，影响美观，如侵袭瞳孔影响视力；三角形翼状胬肉的尖端为头部，角膜缘部位颈部，球结膜上为体部。翼状胬肉的最有效的治疗方式之一为手术治疗，但常规的翼状胬肉切除术出现患者不适感时间较长、结膜、角膜恢复缓慢，切口相对较大等局限性，增加了手术的风险，临床效果不甚理想。有研究指出，翼状胬肉进行改良翼状胬肉切除法不

适感轻，恢复迅速，出血量少，手术时间短，临床效果确切[2]。……