关棱

[摘要] 目的 研究补肾扶脾养血汤佐治肾虚型月经病的效果及对患者生殖激素水平和凝血状态的影响。 方法 將2016年1～12月间我院收治的60例肾虚型月经病患者作为本次研究对象，按照随机数字表法分为两组，30位患者采用雌激素疗法治疗（对照组），30位在对照组基础上加以补肾扶脾养血汤治疗（研究组），观察比较两组患者临床疗效、生殖激素水平和凝血状态。 结果 研究组临床有效率（93.33%）显著优于对照组（73.33%），差异有统计学意义（P<0.05）。治疗后两组患者E2、T、LH及FSH指标均显著升高，且研究组较对照组升高显著（P<0.05）。治疗后两组患者Fib、Vwf及Ps指标均显著下降，且研究组较对照组下降显著（P<0.05）。结论 在肾虚型月经病患者治疗中选择补肾扶脾养血汤可使患者生殖激素水平和凝血状态得到显著改善，提高患者临床疗效，值得在临床上推广使用。

[关键词] 补肾扶脾养血汤；肾虚型月经病；生殖激素；凝血状态

[中图分类号] R271.11 [文献标识码] A [文章编号] 2095-0616（2017）14-73-04

Effect of tonifying kidney and supporting spleen and nourishing blood decoction in adjunctive treatment of kidney-deficiency emmeniopathy and its effect on reproductive hormone level and coagulation state

GUAN Leng

Department of Gynecology and Obstetrics， Maoming Hospital of Traditional Chinese Medicine， Guangdong， Maoming 525000， China

[Abstract] Objective To research effect of tonifying kidney and supporting spleen and nourishing blood decoction in adjunctive treatment of kidney-deficiency emmeniopathy and its effect on reproductive hormone level and coagulation state. Methods 60 patients with kidney-deficiency emmeniopathy who were treated in our hospital from January 2016 to December 2016 were selected as research objects. According to random number table， they were equally divided into two groups. 30 patients were given estrogen therapy （the control group） while other 30 patients were given tonifying kidney and supporting spleen and nourishing blood decoction at basis of the control group （the research group）. Clinical curative effect， reproductive hormone level and coagulation state of patients in two groups were observed and compared. Results Clinical effective rate of the research group （93.33%） was significantly better than that of the control group （73.33%） （P<0.05）. After treatment， E2， T， LH and FSH of patients in two groups were all significantly improved and the research group was more significantly improved compared with the control group （P<0.05）. After treatment， Fib， Vwf and Ps of patients in two groups were all significantly decreased and the research group was more significantly decreased compared with the control group （P<0.05）. Conclusion Tonifying kidney and supporting spleen and nourishing blood decoction in treatment of kidney-deficiency emmeniopathy can significantly improve reproductive hormone level， coagulation state and clinical curative effect， which is worthy of clinical promotion and application.

[Key words] Tonifying kidney and supporting spleen and nourishing blood decoction； Kidney-deficiency emmeniopathy； Reproductive hormone； Coagulation state

女性常见疾病月经病以月经期、量、质、色的异常表现最为突出，本临床观察着重研究月经过少或闭经的月经病。目前認为月经病的重要病因是激素水平不正常，排除全身性或局部生殖器的器质性病变，所以其主要治疗方法是激素治疗[1]。虽然单纯采用雌激素治疗本病时大多数在短时间内就可以取得很好的止血效果，但是，一方面受激素治疗的各种副作用的影响使患者抵触在临床应用上常长时间使用性激素类的药物，不能顺利的配合对此病的治疗，另一方面虽然这些方法能够使患者在短

时间内取得一定的治疗效果，但在停药后往往会使病情反复发作，进而增加治疗的难度[2]。通过我们不断研究发现，中医在治疗月经不调方面有得天独厚的优越性尤其是对治疗肾虚型月经，其以补肾法作为基础，对患者进行综合性的调理，达到促进患者排卵以及月经周期的恢复[3]。……