经方为主治疗透析患者睡眠障碍经验
2017-08-10游培博刘文军
游培博 刘文军
摘要:睡眠障碍是透析患者常见的并发症之一,严重影响患者生活质量及预后。如何改善透析患者的睡眠质量、提高其生活质量和生存率仍是临床一大难题。目前透析患者睡眠障碍的发病机制尚不清楚,西医治疗以镇静催眠类药物为主,但不良反应大,长期使用会出现药效降低且易产生依赖性。中医药在改善透析患者睡眠障碍及生活质量方面疗效确切。本文介绍了以经方为主辨证用药治疗透析睡眠障碍的经验,临床效果显著。
关键词:透析;睡眠障碍;经方;伤寒论
DOI:10.3969/j.issn.1005-5304.2017.08.027
中图分类号:R277.522.5 文献标识码:A 文章编号:1005-5304(2017)08-0113-03
Experience in Treatment of Sleep Disorder of Dialysis Patients with Classic Prescriptions YOU Pei-bo1,2, LIU Wen-jun1 (1. Department of Nephrology, Guanganmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China; 2. Clinical College, Beijing University of Chinese Medicine, Beijing 100029, China)
Abstract: Sleep disorder is a common complication of dialysis patients, seriously affecting the life quality and prognosis of the patients. How to improve the quality of sleep of dialysis patients, their quality of life and survival rate, is still a major clinical problem. At present, the pathogenesis of dialysis patients with sleep disorders is not clear. Western medicine treatment is sedative hypnotic drugs, with obvious adverse reactions, and long-term use will reduce the efficacy and easy to produce dependencies. The effects of TCM on improving sleep disorders and life quality of dialysis patients is worth expectation. This article introduced the experience in using classic prescriptions and dialectical treatment for dialysis sleep disorder, with significant clinical efficacy.
Key words: dialysis; sleep disorder; classic prescriptions; Shang Han Lun
睡眠障碍是血液透析和腹膜透析患者常见的并发症之一。资料显示,透析患者普遍存在睡眠障碍,其发病率高达80%,严重影响患者生活质量与疾病预后[1]。由于透析患者出现睡眠障碍的发病机制尚不清楚,西医治疗有一定的风险,且药物依赖及不良反应较大。笔者以经方为主,辨证治疗透析患者睡眠障碍获得满意疗效,兹结合案例介绍如下。
1 不宁腿综合征致睡眠障碍
案例1:患者,男,34岁,2016年5月11日就诊。患者血液透析4年余。现透析方案:高通量透析,3次/周;联合血液灌流,1次/周。每次透析后静脉注射左卡尼丁1 g。2016年5月6日,透析前检查示:血肌酐(SCr)1156 μmol/L,血尿素氮34 mmol/L,血钙2.39 mmol/L,血磷2.09 mmol/L,血紅蛋白119 g/L,
基金项目:中国中医科学院广安门医院国家中医临床示范基地科研专项暨所级科研基金课题(2013S-01)
通讯作者:刘文军,E-mail:liuwenjunlyzh@sohu.com
血清全段甲状旁腺激素480 pq/mL。血压146/87 mm Hg(1 mm Hg=0.133 kPa),心率76次/min。患者自觉下肢不适感,小腿部尤明显,影响睡眠,需下床行走累后方可入睡,大便偏干,舌淡红,苔黄厚,脉弦细略数。……
