孙兴奎

[摘要] 目的 對比氧驱动雾化吸入和空气压缩泵雾化吸入在小儿喘息治疗的临床效果。 方法 选取 2014年1月～2016年5月本院儿科收治的小儿支气管哮喘160例作为研究对象，随机将其分为对照组与观察组各80例，两组患儿均给予相同药物雾化吸入治疗，对照组采用空气泵雾化吸入方法，观察组应用氧驱动雾化吸入方式，观察两组患儿治疗前后血氧饱和度（SaO2），分别记录两组患儿治疗期间的胸闷咳喘、反复喘息及呼吸困难等临床症状的消失时间，并进行统计学分析。 结果 两组患者治疗后SaO2明显高于治疗前，且两组比较差异有统计学意义（P<0.05）；观察组患者治疗后SaO2明显高于对照组治疗后，且两组比较差异有统计学意义（P<0.05）；观察组患儿咳嗽缓解时间、喘息缓解时间、肺部啰音消失时间、住院时间均显著低于对照组，差异具有统计学意义（P<0.05）；观察组总有效率为96.25%，高于对照组的86.25%，差异有统计学意义（P<0.05）。 结论 氧驱动雾化吸入治疗方式具有起效迅速与疗效显著等临床优势，可广泛推广应用。

[关键词] 小儿支气管哮喘；氧驱动雾化吸入；空气压缩泵雾化吸入；血氧饱和度

[中图分类号] R725.6 [文献标识码] A [文章编号] 2095-0616（2017）10-56-04

Comparative study on curative effect of oxygen atomizing inhalation and air compress pump atomizing inhalation in treatment of pediatric asthma

SUN Xingkui

Department of Pediatrics，Haifeng Pengpai Jinian Hospital，Haifeng 516400，China

[Abstract] Objective To evaluate the clinical curative effect of oxygen atomizing inhalation and air compress pump atomizing inhalation in treatment of pediatric asthma. Methods 160 patients with pediatric bronchial asthma who were admitted to department of pediatrics from January 2014 to May 2016 were selected as research objects and they were randomly divided into the control group and the observation group， with 80 in each.Children in two groups were all given atomizing inhalation of the same drug.The control group was given air compress pump atomizing inhalation while the observation group was given oxygen atomizing inhalation.Blood oxygen saturation （SaO2） before and after treatment of children in two groups was compared.Disappearing time of clinical symptoms such as chest distress，cough and asthma，recurrent wheezing，dyspnea and so on were respectively recorded and statistically analyzed. Results SaO2 after treatment of patients in two groups was significantly higher than that before treatment and comparative difference was statistically significant （P<0.05）.After treatment，SaO2 of patients in the observation group was significantly higher than that of the control group and the difference was statistically significant（P<0.05）.Time for relieving cough，time for relieving asthma，disappearing time for lung rales and hospitalization stay of children in the observation group were all significantly shorter than those of the control group and differences were statistically significant （P<0.05）.The total effective rate of the observation group was 96.25%，higher than that of the control group 86.25% and the difference was statistically significant（P<0.05）. Conclusion Oxygen atomizing inhalation has the advantages of fast onset of action and significant curative effects，which can be widely promoted and applied.

[Key words] Pediatric bronchial asthma；Oxygen atomization inhalation；Air compress pump atomizing inhalation；Blood oxygen saturation

小儿支气管哮喘是儿科中常见呼吸道慢性疾病，主要为慢性气道炎症反应疾病，发病患儿均存在咳嗽、喘息、呼吸困难等临床症状，不但明显影响到儿童生长发育，也会严重危害其生命健康，存在较高临床风险[1]。目前，由于社会、环境等因素的不断变化，该疾病发病情况越发严峻，小儿因持续伴随局部炎症，需长期用药来缓解临床症状并控制疾病进展，而雾化吸入可显著提升用药效果。雾化吸入治疗是一种世界公认的简便快速有效的方法，可以将药物直接作用于病变部位，它不仅仅可以将痰液稀释，消除炎症，同时，它也降低气道的高反应性，解除支气管的痉挛，不断改善通气等优点[2]。通过研究我们发现雾化机的种类越来越多，其优缺点也各有不同，如何选择合理的雾化吸入方法是治疗小儿哮喘的关键。……