张国珍

【摘要】目的 观察参芪扶正液对慢性心力衰竭治疗疗效的观察。方法 观察我院2014年8月～2016年4月住院的慢性心衰患者88例，随机分成两组（对照组和治疗组），对照组采取西医治疗，常规给予利尿，β-受体阻滞剂和ACEI或ARB治疗，观察组在对照组西医治疗有基础上给予参芪扶正液治疗，且β-受体阻滞剂和ACEI或ARB治疗量均达到患者最大耐受量，心率控制在70次或接近70次/分。两组治疗疗程均为两周，通过对患者的症状改善情况，监测BNP的变化及超声监测左室射血分数，每搏输出量有每分输出量的变化结果，来比较两组间的疗效。结果 治疗组患者的症状改善明显，BNP的下降率，左室射血分数、每搏输出量有每分输出量改善明显高于对照组，两组间的差异具（P<0.05）有明显统计学意义。结论 在治疗慢性心力衰竭中，在常规给予利尿，β-受体阻滞剂和ACEI或ARB治疗的基础上给予参芪扶正液疗效更显著。

【关键词】参芪扶正注射液；心力衰竭

【中图分类号】R541 【文献标识码】B 【文章编号】ISSN.2095-6681.2016.36.0.03

Shenqifuzheng Injection Combined with metoprolol tartrate in the treatment of chronic congestive heart failure

ZHANGGuo-zhen

（Inner Mongolia baotou Inner Mongolia baotou iron and steel hospital，NeiMengGu BaoTou 014010，China）

【Abstract】Objective To observe the curative effect of Shenqifuzheng Injection for the treatment of chronic heart failure.Methods To observe the hospital in August 2014 to April 2016，88 cases of chronic heart failure patients in the hospital，randomly divided into 2 groups（control group and treatment group），Control group treated with western medicine，the conventional diuretic，beta blockers and ACEI and ARB therapy，Observation group in the control group based on western medicine have give Shenqifuzheng Injection treatment.And the amount of beta blockers and ACEI and ARB therapy achieves maximum tolerance patients，Heart rate control in 70，or nearly 70 times/min.Two groups of treatment for 2 weeks，Monitoring the change of the BNP and ultrasonic monitoring left ventricular ejection fraction，every cardiac output per minute output changes as a result，to compare the efficacy between the two groups.Results The treatment group of the patient's symptoms improved significantly，the BNP's decline rate，left ventricular ejection fraction，stroke output per minute output improvement is significantly higher than the control group，the difference between two groups（P<0.05） or less had obvious statistical significance.Conclusion In the treatment of chronic heart failure，during routine for diuresis，beta blockers and ACEI and ARB therapy on the basis of ginseng and astragalus centralizer liquid curative effect more remarkable.

心力衰竭是由于心臟的各种结构功能性病变使心室充盈和（或）射血能力受损而引起的一种复杂临床综合征。其具有典型的心力衰竭的症状、体征，且静息状态下有心脏结构或功能异常的客观证据，即在心力衰竭划分阶段中处于C阶段或D 阶段。心力衰竭是所有心血管病的终末阶段。心力衰竭西医治疗的基本方案（或标准方案）应包括3种药物：即利尿剂、β-受体阻滞剂，不能耐受ACEI的患者可应用ARB。西医中利尿剂是消除心力衰竭患者液体潴留的唯一药物，且消除液体潴留使患者处于“干重”状态是使用其它药的基础和前提，ACEI和β-受体阻滞剂的联合可以发挥垒加和协同的有益疗效，是目前治疗心力衰竭的所谓金三角。……