舒守成+敬克晏

摘要：目的 探讨椎管内注射曲安奈德复合液治疗腰椎间盘突出症的临床疗效。方法 选择我院2010年1月～2016年1月收治的100例腰椎间盘突出症患者为研究对象，采用随机奇数偶数法将其分成观察组（n=50例）和对照组（n=50例），观察组患者给予椎管内硬膜外腔注射曲安奈德复合液治疗，对照組采用综合治疗措施，比较观察组与对照组的临床疗效。结果 观察组总有效率为96.00%，对照组总有效率为77.00%，组间差异有统计学意义（P<0.05）；观察组与对照组不良反应发生情况无显著差异（P>0.05）。结论 腰椎间盘突出症患者采用曲安奈德复合液椎管内硬膜外腔注射治疗，具有疗效显著、安全性高、简单、不良反应少，适用于基层医院。

关键词：椎管内注射；曲安奈德；腰椎间盘突出症

Abstract：Objective To investigate the clinical effect of spinal sinus injection in the treatment of lumbar disc herniation.Methods 100 patients with lumbar disc herniation were selected from January 2010 to January 2016.The patients were divided into observation group（n=50 cases）and control group（n=50 cases），by random odd number method.The observation group of patients given spinal epidural injection of triamcinolone acetonide compound solution，the control group using comprehensive treatment measures to compare the observation group and the control group of clinical efficacy.Results The total effective rate was 96.00% in the observation group and 77.00% in the control group，the difference was statistically significant （P<0.05）.There was no significant difference between the observation group and the control group（P>0.05）.Conclusion The patients with lumbar disc herniation treated with triamcinolone acetonide combined with intradermal spinal epidural injection have obvious curative effect，high safety，simple and less adverse reactions，and are suitable for primary hospital.

Key words：Intrathecal injection；Triamcinolone acetonide；Lumbar disc herniation

腰椎间盘突出症是临床常见病，发病机制尤为复杂，主要与腰椎间盘退变或腰部过度负重纤维环过度受压变性形成瘢痕有关。瘢痕压迫相应神经，则形成压痛，同时又出现弥漫性疼痛症状；退行性纤维环松驰，多次受压时突出椎体边缘，使硬脊膜相应部位神经根受压、神经根及周围组织发生无菌性炎变，引起静脉丛充血、神经根缺血而引起疼痛。研究显示，大多数患者采用非手术治疗方式进行治疗，均可有效地缓解或者消除症状，甚至能完全治愈腰椎间盘突出症[1]。本次研究笔者对腰椎间盘突出症患者治疗的复合液是曲安奈德20 mg加入维生素B1注射液100 mg、维生素B12注射液2ml、维生素B6注射液100 mg、2%利多卡因注射液5 ml、加入适量的0.9%氯化钠液配成20 ml混合液进行椎管内硬膜外腔注射治疗，取得较好疗效，现报道如下。……