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颈动脉超声和经颅多普勒超声联合评价颈动脉狭窄支架治疗的临床效果

2017-03-28张逊娟

中国实用医药 2017年5期

张逊娟

【摘要】 目的 探討颈动脉超声和经颅多普勒超声联合评价颈动脉狭窄支架治疗的临床效果。方法 65例行颈动脉狭窄支架治疗患者, 均采用颈动脉超声和经颅多普勒超声对颈动脉狭窄局部管径、狭窄段收缩期峰值流速、同侧大脑中动脉的收缩期峰值流速、搏动指数进行检测, 分析对比检测结果。结果 术前颈动脉狭窄处管腔内径、收缩期峰值流速分别为(3.2±0.8)mm、(190.4±78.2)cm/s;术后1周分别为(4.8±0.6)mm、(87.3±30.6)cm/s;术后1年分别为(4.7±0.5)mm、(90.3±29.8)cm/s。术后1周、1年颈动脉狭窄处管腔内径、收缩期峰值流速均优于术前, 差异具有统计学意义(t1周=12.900、9.899, t1年=12.819、9.644, P<0.05)。术前患侧大脑中动脉收缩期峰值流速、血管搏动指数分别为(78.7±14.7)cm/s、(0.9±0.1);术后1周分别为(114.3±23.2)cm/s、(1.1±0.2);术后1年分别为(110.8±20.8)cm/s、(1.1±0.4)。术后1周、1年患侧大脑中动脉收缩期峰值流速、血管搏动指数均优于术前, 差异具有统计学意义(t1周=10.450、7.211, t1年=10.161、3.911, P<0.05)。结论 颈动脉超声联合经颅多普勒超声适用于颈动脉狭窄支架治疗效果评价, 值得推广。

【关键词】 颈动脉超声;经颅多普勒超声;颈动脉狭窄支架

DOI:10.14163/j.cnki.11-5547/r.2017.05.020

Clinical effect of combined evaluation by carotid artery ultrasound and transcranial Doppler ultrasound on carotid artery stenosis stent treatment ZHANG Xun-juan. Jilin Provincial Peoples Hospital, Changchun 130021, China

【Abstract】 Objective To investigate clinical effect by carotid artery ultrasound and transcranial Doppler ultrasound in evaluation of carotid artery stenosis stent treatment. Methods A total of 65 patients receiving carotid artery stenosis stent treatment all received examination by carotid artery ultrasound and transcranial Doppler ultrasound for carotid artery stenosis local blood vessel diameter, stenosis peak systolic flow velocity, ipsilateral middle cerebral artery peak systolic flow velocity, and pulsatility index. Comparison and analysis were made on examination outcomes by the two measures. Results Preoperative carotid artery stenosis local blood vessel diameter and peak systolic flow velocity were respectively (3.2±0.8) mm and (190.4±78.2) cm/s,

which were (4.8±0.6) mm, (87.3±30.6) cm/s in postoperative 1 week, and (4.7±0.5) mm, (90.3±29.8) cm/s

in postoperative 1 year. Postoperative carotid artery stenosis local blood vessel diameter and peak systolic flow velocity in 1 week and 1 year were all better than those before operation, and the difference had statistical significance (t1week=12.900, 9.899, t1year=12.819, 9.644, P<0.05). Preoperative ipsilateral middle cerebral artery peak systolic flow velocity and pulsatility index were respectively (78.7±14.7) cm/s and (0.9±0.1), which were (114.3±23.2) cm/s, (1.1±0.2) in postoperative 1 week, and (110.8±20.8) cm/s, (1.1±0.4) in postoperative 1 year. Postoperative ipsilateral middle cerebral artery peak systolic flow velocity and pulsatility index in 1 week and 1 year were all better than those before operation, and the difference had statistical significance (t1week=10.450, 7.211, t1year=10.161, 3.911, P<0.05). Conclusion Combination of carotid artery ultrasound and transcranial Doppler ultrasound is worth promoting in evaluation of carotid artery stenosis stent effect.

【Key words】 Carotid artery ultrasound; Transcranial Doppler ultrasound; Carotid artery stenosis stent

研究发现, 颈动脉狭窄是当前学界公认的缺血性脑血管病重要危险因子, 临床常采用颈动脉支架置入术进行治疗, 能够有效降低患者脑卒中的发生风险[1-3]。超声检测是一种无创性检查手段, 将其应用于颈动脉狭窄疾病患者诊断与疗效评估具有重要的临床价值[4]。据此本研究中以65例行颈动脉狭窄支架治疗患者为例, 主要探讨颈动脉超声联合经颅多普勒超声对疾病评估的应用效果, 现将结果报告如下。

1 资料与方法

1. 1 一般资料 选取本院2014年1月~2015年8月收治的65例行颈动脉狭窄支架治疗患者作为研究对象。其中男41例,

女24例;平均年龄(62.2±4.1)岁;合并病症:高血压31例, 糖尿病19例, 高脂血症15例。纳入标准:所有患者均签署知情同意书;经检查均符合颈动脉狭窄支架治疗的适应证。排除标准:存在手术禁忌证、对造影剂过敏、颈内动脉完全闭塞等患者[5]。……

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