β—HCG比值联合子宫内膜厚度预测早期不明位置妊娠者异位妊娠的临床价值
2016-11-26芦笛杨娜任永变李红梅
芦笛+杨娜+任永变+李红梅

【摘要】目的:探讨β-HCG比值联合子宫内膜厚度对早期不明位置妊娠者异位妊娠的预测价值。方法:从我院2011年2月至2014年12月间产生的妊娠病例中随机选择151例,回顾分析孕妇的血清β-HCG比值以及子宫内膜厚度检测方法及结果,并比较应用该种检测方法诊断宫内妊娠正常、妊娠异常以及异位妊娠孕妇的诊断符合率。结果:异位妊娠孕妇的血清β-HCG比值明显低于宫内妊娠正常孕妇,其差异具有统计学意义(P<0.05);异位妊娠孕妇子宫内膜厚度小于宫内妊娠正常孕妇,其差异具有统计学意义(P<0.05)。此外,妊娠异常孕妇的血清β -HCG比值以及子宫内膜厚度值均小于宫内妊娠正常孕妇,其差异具有统计学意义(P<0.05)。血清β-HCG比值联合子宫内膜厚度检测的诊断符合率明显高于单项血清β-HCG比值或子宫内膜厚度检测,其差异具有统计学意义(P<0.05)。此外,血清β-HCG比值以及子宫内膜厚度的诊断方法在异位妊娠检查中的诊断符合率要高于妊娠正常及妊娠异常两类,其差异具有统计学意义(P<0.05)。结论:联合β-HCG比值和子宫内膜厚度两项指标进行判断,能够在早期不明位置妊娠者异位妊娠的检测过程中发挥比较准确的预测作用,具有较高的诊断价值;同时这两项判断指标仅需联用非侵入性检测技术就能达到有效检测的目的,是妇产科检测中一种安全系数高、真实准确、值得推广的方法。
【关键词】β-HCG比值;子宫内膜厚度;早期不明位置;异位妊娠;预测
【Abstract】Objectives: To explore the predictive value ofβ-hCG ratio joint endometrial thickness for early ectopic pregnancy of unknown location. Methods: 151 pregnant women in our hospital from February 2011 to December 2014 were randomly selected, and the clinical examination and diagnosis methods and results were retrospectively analyzed, to compare the diagnostic accordance rate for normal pregnancy, abnormal pregnancy and ectopic pregnancy. Results: The serum beta HCG ratio of ectopic pregnant women was significantly lower than normal pregnant women, with statistically significant difference (P< 0.05). The endometrial thickness of ectopic pregnant women was significantly less than normal pregnant women, with statistically significant difference (P< 0.05). The beta HCG ratio and endometrial thickness of abnormal pregnant women were less than the normal pregnant women, with statistically significant difference (P< 0.05). The joint diagnosis accordance rate of serum beta HCG ratio and endometrial thickness was obviously higher than either alone, with statistically significant difference (P< 0.05). In addition, the joint diagnosis accordance rate of ectopic pregnancy was higher than normal pregnancy and abnormal pregnancy, with statistically significant difference (P< 0.05). Conclusion: Joint use of beta hCG ratio and endometrial thickness is of remarkable value in the prediction of early ectopic pregnancy of unknown location. Combined with non-invasive detection technology, it is an effective detection method with high safety and accuracy, which is worth promoting.
【Key words】Beta hCG ratio; Endometrial thickness; Early unknown location; Ectopic pregnancy; Prediction
【中图分类号】R714.22【文献标志码】A
早期不明位置妊娠一般指4~6周孕周的孕妇经妊娠试验结果呈阳性,但超声检查过程中并未发现有宫内孕囊的一种情况,临床医学统计表明,该种情况的发生率8%以上[1]。异位妊娠作为产科中比较常见的急腹症,是引起孕妇死亡的主要原因之一。由于异位妊娠的早期诊断缺乏相关的敏感性指标,异位妊娠常常被视为早期妊娠的高危并发症。本文从我院2011年2月至2014年12月间产生的妊娠病例中随机选择151例,着重探讨了β-hCG比值联合子宫内膜厚度对早期不明位置妊娠者异位妊娠的预测价值,得出的结果报道如下。endprint
1资料与方法
1.1基本资料
本次研究随机选择151例早期妊娠病例中的患者,均符合以下条件:经过了妊娠试验或者血清检测,全部孕妇的妊娠试验结果显示为阳性,或者血清β-HCG的检测值大于10U/L;停经34~56d,平均停经(40.3±0.5)d;TVS结果显示未发现有宫内孕囊,未显示盆腔有明显积血;……
