陈海挺 胡江飚 卢敏攀 宁维翾

【摘要】目的：探讨金银花汤联合青霉素治疗梅毒效果。方法：选取2013年1月至2015年1月于我院与杭州市中医院接受治疗的120患者为研究对象，按照自愿原则，将其均分为观察组和对照组。对照组单纯采用青霉素进行治疗；观察组采用金银花汤联合青霉素进行治疗。比较两组随访结果及治疗有效率。结果：观察组平均有效时间为（0.79±0.23）d，平均治愈时间为（2.47±0.29）d，PRP转阴率为91.67%；对照组分别为（1.61±0.27）d、（3.52±0.44）d、70.00%，观察组随访结果明显优于对照组（P<0.05）。两组患者病情均有一定程度的改善，其中观察组中显效的有52例，有效的有3例，无效的仅有5例，而对照组相应为25例、17例、18例，对照组治疗有效率明显低于观察组（P<0.05）。结论：金银花汤联合青霉素能有效缩短痊愈时间、提高PRP转阴率、提升治疗有效率，临床效果显著。

【关键词】金银花汤；青霉素；梅毒；效果观察

Effect of honeysuckle soup with penicillin in the treatment of syphilisCHEN Haiting1， HU Jiangbiao1， LU Minpan1， NING Weixuan2. 1. Department of Rehabilitation Medicine of Chinese Medicine，Yongkang First Peoples Hospital， Jinhua 321300， Zhejiang， China； 2. Dermatology Department，Hangzhou Traditional Chinese Medical Hospital， Hangzhou 310000， Zhejiang， China

【Abstract】Objectives： To explore the effect of honeysuckle soup combined penicillin in the treatment of syphilis. Methods： 120 patients in Yongkang First Peoples Hospital and Hangzhou Traditional Chinese Medical Hospital from January 2013 to January 2015 were selected as research objects， and in accordance with the principle of voluntary， were divided into observation group and control group. Control group simply received penicillin treatment； while the observation group received honeysuckle soup combined penicillin treatment. The treatment effectiveness and follow-up results were compared between the two groups. Results： The average effective time， average healing time and PRP negative conversion ratio in observation group were （0.79±0.23） d， （2.47±0.29） d and 91.67% respectively， while those in the control group were （1.61±0.27）d， （3.52±0.44） d and 70.00% accordingly. The follow-up results of observation group were obviously better than that of control group （P<0.05）. The condition of patients in both groups was improved to a certain extent， where 52 cases took effect， 3 cases proved effective and 5 cases ineffective in the observation group， and those in the control group were 25 cases， 17 cases and 18 cases respectively， with significant difference between the two groups （P<0.05）. Conclusion： Honeysuckle soup combined penicillin can effectively shorten the healing time， increase the PRP negative conversion ratio and promote efficient treatment， with remarkable treatment effect.

【Key words】Honeysuckle soup； Penicillin； Syphilis； Results observation

【中图分类号】R759.1【文献标志码】A

梅毒是一种慢性传染性疾病，属于多器官疾病，其传播媒介是苍白螺旋体，传播途径主要是直接或间接的性接触、母婴传播、输血等[1]。研究表明，目前我国梅毒的发病情况呈现上升趋势，梅毒由于其传染性给患者的生活带来了极大的不便，也给患者带来了极大的精神压力，严重影响患者的生活质量和健康状况[2]。目前治疗梅毒的常用药物主要是苄星青霉素、头孢三嗪等，为了探讨金银花汤联合青霉素治疗梅毒效果，我院尝试开展本研究。现报道如下。

1资料与方法

1.1一般性资料

选取2013年1月至2015年1月于我院与杭州市中医院皮肤科接受治疗的患者为研究对象，按照自愿原则，将其均分为观察组和对照组，每组患者60例。纳入标准：（1）所有患者均符合卫生部防疫司《性病防治手册》中梅毒的临床诊断标准；（2）经过实验室根据患者体征及实验室检测RPR、梅毒螺旋体抗体明胶颗粒试验（TPPA）均为阳性；……