洪恽+陈军

【摘要】目的：分析并探讨经直肠超声造影辅助前列腺穿刺活检与前列腺系统穿刺活检的差异。方法：选取2010年1月至2015年5月期间在我院接受治疗的可疑前列腺癌患者300例，分为观察组和对照组，每组150例。观察组采用经直肠前列腺超声造影辅助前列腺穿刺活检，对照组则采用系统的前列腺12针穿刺活检。结果：观察组前列腺癌57例，占38.00%，人均穿刺（9.3±1.4）针，单针阳性率为18.21%，Gleason评分为（7.1±0.5）分。对照组前列腺癌54例，占35.33%，人均穿刺12针，单针阳性率为11.17%，Gleason评分为（6.6±0.5）分。两组前列腺癌诊断率无显著差异，观察组其他各项指标明显优于对照组，经统计学检验，差异具有统计学意义（P<0.05）。观察组造影异常70例（46.7%），确诊前列腺癌41例，人均穿刺（6.19±0.7）针，单针阳性率为43.91%（191/435）；观察组造影正常80例（53.3%），确诊前列腺癌16例，人均穿刺12针，单针阳性率为6.56%（63/960）。结论：经直肠超声造影辅助前列腺穿刺活检与前列腺系统穿刺活检相比效率更高，临床上值得推广。

【关键词】前列腺穿刺活检；超声造影；超声

Comparative study of trans-rectal ultrasound contrast-assisted prostate biopsy and prostate system biopsyHONG Yun1， CHEN Jun2. 1.Department of Urology， Wenling Fourth Peoples Hospital， Taizhou 317511， Zhejiang， China； 2.Department of Urology， Wenling First Peoples Hospital， Taizhou 317500， Zhejiang， China

【Abstract】Objectives： To analyze and discuss the differences between trans-rectal ultrasound contrast-assisted prostate biopsy and prostate system biopsy. Methods： 300 cases of suspected prostate cancer treated in in Wenling City Fourth Peoples Hospital from January 2010 to May 2015 were selected and divided into two groups as control group and observation group， with 150 cases in each group. Observation group received trans-rectal ultrasound-assisted prostate biopsy and control group received 12 prostate needles biopsy. Results： There were 57 cases of prostate cancer in observation group， accounting for 38.00%， per capita puncture （9.3 ± 1.4）. Single needle positive rate was 18.21% and Gleason score was （7.1 ± 0.5） points. There were 54 cases of prostate cancer in control group， accounting for 35.33%， per capita puncture （12）. Single needle positive rate was 11.17% and Gleason score was （6.6 ± 0.5） points. There were no significant differences in prostate cancer diagnosis between observation group and control group. Other indicators in observation group were better than these in control group， with statistically significant difference （P<0.05）. There were 70 cases of abnormal radiography in observation group （46.7%）， with 41 cases of prostate cancer and per capita puncture （6.19 ± 0.7）. Single needle positive rate was 43.91% （191/435）； in observation group， there were 80 cases of normal radiography （53.3%）， with 16 cases of prostate cancer and per puncture （12）. Single needle positive rate was 6.56% （63/960）. Conclusion： Trans-rectal ultrasound contrast-assisted prostate biopsy is more efficient than prostate system biopsy， which is worth promoting in clinic.endprint

【Key words】Prostate biopsy； Ultrasound contrast； Ultrasound

【中图分类号】R737.25【文献标志码】A

前列腺癌是一种常见的男性前列腺上皮恶性肿瘤，早期发现、及时治疗可有效提高患者5年内生存率，改善患者生存质量[1]。目前临床中普遍应用前列腺穿刺活检对前列腺癌进行诊断，随着科技的逐步发展，穿刺活检中可伴随多种方式进行引导，从而提高穿刺成功率[2]。超声引导是最常见的辅助引导穿刺方式，但据报道显示经直肠超声引导所需穿刺针数多，给患者带来较大痛苦，因此如何适当改善超声引导使其保证诊断率的同时降低所需穿刺数将提高患者依从性，降低其诊断痛苦[3]。在本次研究中，选取2010年1月至2015年5月期间来我院接受治疗的可疑前列腺癌患者300例，分析并探讨经直肠超声造影辅助前列腺穿刺活检与前列腺系统穿刺活检的差异。……