谢春雷

沭阳县中心医院皮肤性病科，江苏宿迁223600

潜伏梅毒发病率上升趋势原因分析

谢春雷

沭阳县中心医院皮肤性病科，江苏宿迁223600

目的观察并讨论潜伏梅毒的临床相关因素，以期降低梅毒发病率及感染艾滋病的风险。方法选取2012年12月—2015年12月来该院治疗的150例潜伏梅毒患者资料进行归纳和整理，对患者展开血清学检测、就诊原因及诊治情况分析。结果经分析得知，女性潜伏梅毒患者明显高于男性患者，所有患者血清RPR滴度为1：1～1：128；患者在治疗3个月、6个月后RPR阴转率无明显差异（P＞0.05）；患者在治疗3个月后IgM阴转率为38.7%，治疗6个月IgM阴转率为18.0%，患者IgM转阴率存在显著差异（P＜0.05），具有统计学意义。结论对潜伏梅毒患者施以严格血清学检测评估并由此开展治疗，重视对潜伏患者的追踪检测，对降低临床的潜伏梅毒发病率具有显著意义，值得加大临床的推广。

潜伏梅毒；血清学；分析观察；研究

［Abstract］Objective To observe and discuss the clinical related factor of latent syphilis in order to reduce the incidence rate of syphilis and infection risks of AIDS.Methods The data of 150 cases of patients with latent syphilis treated in our hospital from December 2012 to December 2015 were summarized，and the patients were given serology detection，and the diagnosis causes and situations were analyzed.Results The analysis showed that the female patients with latent syphilis were obviously higher than those in male patients，the serum RPR titer of all patients was between 1：1 to 1：128，after 3-month and 6-month treatment，there was no difference in the RPR negative conversion rate，P＞0.05，and there was an obvious difference in the IgM negative conversion rate after 3-month and 6-month treatment with statistical significance，P＜0.05.Conclusion We should implement the strict serology detection evaluation and then carry out treatment for patients with latent syphilis，and it is of obvious significance to reduce the incidence rate of latent syphilis in clinic that paying attention to the tracing detection，which is worth great promotion in clinic.

［Key words］Latent syphilis；Serology；Analysis and observation；Research

近些年来，国内临床潜伏梅毒的发病率始终呈逐年递升的态势，且增长迅速［1］。潜伏梅毒一般无临床特异性，然而其危害性仍需引起足够重视，该病也常称之为复发性梅毒，一旦治疗或控制不当，则会发展成晚期梅毒，给患者造成不可逆转损害［2］。潜伏梅毒因无其他疾病所表现出的临床特征，故而早期难以被发现，对患者健康有极大危害。随着现代临床血清学检测技术的不断快速发展和筛查力度的加强，通过血清学诊断出的潜伏梅毒的病例也更为确实可靠，对梅毒的治疗和防控有着重要的现实意义。……