反流性胃炎的临床治疗
2016-10-21程大勇袁建喜
程大勇 袁建喜
【摘要】 目的:探讨反流性胃炎的临床治疗。方法:选取164例反流性胃炎,随机分为治疗组78例和对照组86例,治疗组给予胃复安、痢特灵、替硝唑三联治疗;对照组给予胃复安、胆酪胺、胃得宁治疗,两组疗程均为3周,疗程结束后复查胃镜。结果:治疗组治愈率89.7%,总有效率100%,对照组治愈率37.2%,总有效率77.9%,两组比较差异有统计学意义(P<0.01),1年后治疗组复发率3.8%,对照组15.1%,两组比较差异有统计学意义(P<0.01)。结论:胃复安、痢特灵、替硝唑三联治疗反流性胃炎,疗效确切,无明显毒副作用,药源广,价格低,适用于基层乡镇医院推广应用。
【关键词】 反流性胃炎; 幽门螺杆菌; 诊断; 治疗
中图分类号 R573.3 文献标识码 B 文章编号 1674-6805(2016)6-0110-02
The clinical Treatment of Reflux Gastritis/CHENG Da-yong,YUAN Jian-xi.//Chinese and Foreign Medical Research,2016,14(6):110-111
【Abstract】 Objective:To study the diagnosis and treatment of reflux gastritis.Method:164 patients with back flow gastritis were welected,they were randomly divided into the treatment group(78 cases) and the control group(86 cases),the treatment group were treated with Metoclopramide,Furazolidone,Tinidazole triple therapy;the control group was treated with Metoclopramide,Cholestyramine,Weidening Tablet in the treatment.The course of treatment in the two groups were 3 weeks,after the end of treatment gastroscop was reexamined.Result:The cure rate of the treatment group was 89.7%,the total effective rate was 100%,the cure rate of the control group was 37.2%,the total effective rate was 77.9%,there were significantly different in two groups(P<0.01),1 year after the recurrence rate of the treatment group was 3.8%,the control group was 15.1%,and the two groups had significant difference(P<0.01).Conclusion:Metoclopramide, Furazolidone,Tinidazole triple therapy return gastritis are curative effect,no obvious toxic and side effects,drug source wide,low price for to the grass-roots level to promote the application of the township hospitals.
【Key words】 Reflux gastritis; Helicobacter pylori; Diagnosis; Treatment
First-authors address:Cao County Wangji Town Health Center,Cao County 274400,China
doi:10.14033/j.cnki.cfmr.2016.6.060
近年來随着对幽门螺杆菌(Hp)研究的进展,对Hp与反流性胃炎的关系有了比较明确的认识,对反流性胃炎的诊断与治疗有了新的进展。随着抗菌药及新型胃动力药的应用,患者治愈率明显提高,复发率明显下降,现将反流性胃炎的诊断与治疗,结合病例分析报告如下。
1 资料与方法
1.1 一般资料
本组164例均为笔者所在医院2013年3月-2014年8月经胃镜确诊并排除伴有其他疾病的住院患者,全部病例诊断符合反流性胃炎的诊断标准[1]。男146例(89.1%),女18例(10.9%),男女之比为8∶1;年龄15~62岁,平均(42.3±3.6)岁,其中15~45岁136例。病程2个月~2年,平均(1.3±0.3)年。长期饮酒者76例(46%),长期吸烟者116例(70.9%)。临床症状及体征见表1。随机将患者分为两组。治疗组78例,其中男69例,女9例,年龄15~61岁,平均(43.5±3.8)岁,其中15~45岁67例,病程2个月~2.8年,平均(1.4±0.5)年;对照组(传统治疗组)86例,其中男77例,女9例;年龄16~62岁,平均(44.4±3.7)岁,15~45岁136例,病程2个月~2.7年,平均(1.5±0.4)年。两组患者性别、年龄、病程、临床症状体征比较差异无统计学意义(P>0.05),具有可比性,见表1。
1.2 治疗方法
两组均戒烟酒、规律生活、忌辛辣刺激性食物。两组疗程均为3周,疗程结束后复查胃镜。……p>
