朱艳霞 甄宁 吕冬芳 王雪笠

[摘要] 目的 探討生物反馈疗法对帕金森病患者情绪的改善作用。 方法 选取2013年10月～2014年10月白求恩国际和平医院诊治的帕金森病患者56例，采用随机数字表法分为两组，每组各28例。对照组患者实施常规治疗，观察组患者实施生物反馈疗法治疗。于治疗前后分别行汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）、帕金森病统一评分量表（UPDRS）评分。比较两组患者的治疗效果。 结果 治疗后，两组患者焦虑程度、抑郁程度均明显减轻，HAMA评分（躯体性焦虑、精神性焦虑、总评分）、HAMD评分（焦虑、体重、认知障碍、日夜变化、迟缓、睡眠障碍、绝望感、总评分）、UPDRS评分（精神行为和情绪、日常生活能力、运动检查、治疗的并发症、修订的HOEHN&YAHR分级、SCHWAB&ENGLAND日常活动能力量表）均显著降低，差异均有统计学意义（P < 0.05）。治疗后，观察组患者焦虑程度、抑郁程度均明显低于对照组，差异均有统计学意义（P < 0.05）；HAMA评分（躯体性焦虑、精神性焦虑、总评分）、HAMD评分（焦虑、体重、认知障碍、日夜变化、迟缓、睡眠障碍、绝望感、总评分）、UPDRS评分（精神行为和情绪、日常生活能力、运动检查、治疗的并发症、修订的HOEHN&YAHR分级、SCHWAB&ENGLAND日常活动能力量表）均明显低于对照组，差异均有统计学意义（P < 0.05）。 结论 生物反馈疗法可明显改善帕金森病患者的情绪状况。

[关键词] 生物反馈疗法；帕金森病；情绪

[中图分类号] R651 [文献标识码] A [文章编号] 1673-7210（2016）03（a）-0012-05

Improvement effect of biological feedback therapy on emotion of patients with Parkinson disease

ZHU Yanxia ZHEN Ning LU Dongfang WANG Xueli

Department of Neurology， Bethune International Peace Hospital， Hebei Province， Shijiazhuang 050082， China

[Abstract] Objective To investigate improvement effect of biological feedback therapy on emotion of patients with Parkinson disease. Methods 56 Parkinson disease patients from October 2013 to October 2014 in Bethune International Peace Hospital were selected， who were randomly divided into two groups， 28 patients in each group. Control group was received routine treatment， and observation group was received biological feedback therapy. All patients were evaluated by Hamilton anxiety scale （HAMA）， Hamilton depression scale （HAMD）， unified Parkinson disease rating scale （UPDRS） before and after treatment. Treatment effect was compared between two groups. Results After treatment， degree of anxiety and depression reduced significantly， while HAMA score （somatic anxiety， mental anxiety， total score）， HAMD score （anxiety， body weight， cognitive impairment， diurnal variation， retardation， sleep disorders， despair sense， total score） UPDRS score（mental behavior and emotion， ability of daily life， motor examination， treatment of complications， revision of HOEHN&YAHR grading， SCHWAB&ENGLAND activities of daily living scale） decreased significantly in two groups， the differences were statistically significant （P < 0.05）. After treatment， degree of anxiety and depression in observation group were significantly lower than control group， the differences were statistically significant （P < 0.05）； HAMA score （somatic anxiety， mental anxiety， total score）， HAMD score （anxiety， body weight， cognitive impairment， diurnal variation， retardation， sleep disorders， despair sense， total score）， UPDRS score （mental behavior and emotion， ability of daily life， motor examination， treatment of complications， revision of HOEHN&YAHR grading， SCHWAB&ENGLAND activities of daily living scale） in observation group were significantly lower than control group， the differences were statistically significant （P < 0.05）. Conclusion Biological feedback therapy can significantly improve emotion of patients with Parkinson disease.

[Key words] Biological feedback therapy； Parkinson disease； Emotion

帕金森病是一种发生于中老年的神经系统退行性疾病[1-2]，主要的临床表现为静止性震颤、肌强直、运动迟缓和姿势步态异常等。患者多伴有不同程度的睡眠障碍[3-4]，这会明显影响到患者的心理状况、生理状况，显著降低患者的生活质量[5-6]。生物反馈疗法利用现代生理科学仪器，通过人体内生理或病理信息的自身反馈，使患者经过特殊训练后，进行有意识的“意念”控制和心理训练，通过学习达到随意调节自身躯体功能的目的，从而消除病理过程，恢复身心健康[7-8]。为了探讨生物反馈疗法对帕金森病患者情……