空蝶鞍发生率与年龄、性别相关性的MRI研究
2016-09-19付民峰许宏霞
付民峰,许宏霞
(山东省邹城市人民医院①放射科,②中医科,山东 邹城 273500)
空蝶鞍发生率与年龄、性别相关性的MRI研究
付民峰1,许宏霞2
(山东省邹城市人民医院①放射科,②中医科,山东 邹城 273500)
目的:应用MRI探讨空蝶鞍的发生率及其与年龄、性别的相关性。方法:对连续4 000例行头颅MRI检查且无梗阻性脑积水患者资料进行回顾性分析,年龄10~89岁,平均53岁。按性别及年龄进行分组,观察空蝶鞍的发生率并进行统计分析。结果:4 000例中空蝶鞍233例,发生率为5.82%,10~19、20~29、30~39、40~49、50~59、60~69、70~79和80~89岁年龄组空蝶鞍的发生率依次为0(0/214)、0.92%(2/217)、3.22%(14/435)、5.70%(34/597)、6.34%(41/647)、7.24%(56/773)、7.67%(58/756)和7.76%(28/361)。男女空蝶鞍发生率分别为3.76%(74/1 967)和7.82%(159/2 033),差异有统计学意义(χ2=30.024,P=0.000)。40~49、50~59、60~69、70~79、80~89岁年龄组空蝶鞍发生率女性均高于男性(均P<0.05)。结论:空蝶鞍发生率随年龄增长而升高,且男性低于女性。根据空碟鞍典型MRI表现,结合临床不难作出诊断。
垂体;空蝶鞍;发生率;磁共振成像
[Abstract]Objective:To explore the incidence of empty sella using MRI and its correlation with age and gender.Methods:Brain MR images of 4 000 consecutive subjects(age range,10~89 years;mean age,53 years)without obstructive hydrocephalus were analyzed retrospectively.Incidence of empty sella in different sex and age groups were recorded and statistical analyzed. Results:Empty sella were found in 233 of 4 000 patients,the total incidence of empty sella was 5.83%.The incidence of empty sella for male and female were 3.76%(74/1967)and 7.82%(159/2 033)(χ2=30.024,P=0.000),respectively.The incidence of empty sella for groups of age 10~19,20~29,30~39,40~49,50~59,60~69,70~79 and 80~89 was 0% (0/214),0.92% (2/ 217),3.22% (14/435),5.70% (34/597),6.34% (41/647),7.24% (56/773),7.67% (58/756)and 7.76% (28/361),respectively. The incidence of empty sella was higer in females than in males in all groups except group of age 10~19.Conclusion:The total incidence of empty sella was 5.83%,which increases with age.The incidence of empty sella is lower in males than in females.
[Key words]Pituitary gland;Empty sella;Incidence;Magnetic resonance imaging
空蝶鞍是蝶鞍的一种解剖异常[1],临床上并非少见,发生率4%~94%[2-7]。多数空蝶鞍并无重要的临床意义,若伴头痛、视力减退、高血压及垂体内分泌异常等临床症状时,则称为症状性空蝶鞍、原发性或特发性空蝶鞍综合征(primary empty sella syndrome,PESS)[8-9]。随着MRI的普及,空蝶鞍的检出率明显提高。为了加深对空蝶鞍的认识,现回顾性分析连续4 000例患者的头颅MRI图像,以探讨中国人群中空蝶鞍的发生率及其与性别、年龄之间的关系,为临床提供参考。
1 资料与方法
1.1一般资料搜集2014年1—12月我院所有行头颅MRI检查患者共4 000例,男1 967例,女2 033例;年龄10~89岁,平均53岁。分为10~19、20~29、30~39、40~49、50~59、60~69、70~79和80~89岁8个年龄组。入选标准:①无梗阻性脑积水;②无固定的假牙或其他金属牙齿填充物;……
