李元塔，周广裕，莫俊德（广东省湛江中心人民医院内科ICU，广东　湛江524037）

主动脉内球囊反搏术在脓毒性休克中的临床应用

李元塔，周广裕，莫俊德
（广东省湛江中心人民医院内科ICU，广东湛江524037）

目的：分析主动脉内球囊反搏术在脓毒性休克中的临床应用。方法：选取本院收治的62例脓毒性休克患者并按随机数字表法分为对照组和观察组，各31例患者。对照组患者采用脓毒症指南规范抗休克方法治疗，观察组患者在规范抗休克基础加用主动脉内球囊反搏术治疗。对比2组患者治疗后血压、心率、尿量的变化，及不良事件的发生情况。结果：观察组治疗后血压、心率、尿量改善明显优于对照组（P＜0.05）；观察组治疗后不良事件的总发生率（16.13％）明显低于对照组（45.16％）（P＜0.05）。结论：脓毒性休克的患者采用主动脉内球囊反搏术的临床效果显著，明显改善了患者的血压、心率，使尿量增加，且不良事件发生少，安全有效。

脓毒性休克；主动脉内球囊反搏术；临床效果

doi：10.16753/j.cnki.1008-2344.2016.04.013

［Abstract］Objective：To analyze clinical application of intra⁃aortic balloon pump in the treatment of septic shock.Methods：A total of 62 patients with septic shock in our hospital were assigned into the control group and the observation group according to digital table method，with 31 cases in each group.Patients in the control group were treated with conventional antishock method and patients in the observation group were given intra⁃aortic balloon pump therapy based on the treatment.Blood pressure，heart rate，urine volume and adverse event in the two groups were compared after treatment.Results：After treatment，blood pressure，heart rate and urine volume of the observation group were improved significantly compared with that in the control group（P＜0.05）.The overall incidence of adverse events in the observation group（16.13％）was significantly lower than that in the control group （45.16％）after treatment（P＜0.05）.Conclusion：Intra-aortic balloon pump therapy exerts obvious effect in the treatment of septic shock，significantly improves the patient's blood pressure and heart rate，increases urine volume，causes less adverse events，and is safe and effective.

［Key words］septic shock；intra⁃aortic balloon pump；clinical effect

脓毒性休克是急危重症患者常见的死亡原因［1］。临床上多采用主动脉内球囊反搏术促进心排出量，以辅助左心室功能为主，心室舒张期充气可增加主动脉的压力和冠状动脉的灌流，收缩期放气使心脏后负荷急剧下降，使心搏出量在心脏指数不变的情况下有所增加［2］。为探讨该治疗方案在脓毒性休克辅助循环方面的临床应用效果，现将我院收治的脓毒性休克患者的结果报道如下。

1　资料与方法

1.1一般资料选取2014年12月至2015年12月我院收治的62例脓毒性休克患者为研究对象，所有患者根据实验室诊断及临床症状表现均确诊为脓毒性休克［3］。……