宫腔镜电切联合屈螺酮炔雌醇治疗子宫内膜息肉的临床观察
2016-08-24黄惠君广东省阳春市妇幼保健院广东阳春529600
黄惠君(广东省阳春市妇幼保健院,广东 阳春529600)
宫腔镜电切联合屈螺酮炔雌醇治疗子宫内膜息肉的临床观察
黄惠君
(广东省阳春市妇幼保健院,广东阳春529600)
目的:探究宫腔镜电切联合屈螺酮炔雌醇治疗子宫内膜息肉的临床效果。方法:选取2014年2月至2015年12月来我院治疗的80例子宫内膜息肉患者为研究对象,对照组给予宫腔镜手术治疗,术后静脉滴注缩宫素和抗生素。观察组在对照组的基础上给予口服屈螺酮炔雌醇片,1片/d,连续服用3周,共治疗3个周期。术后4个月行门诊随访,记录疗效及并发症的状况。结果:2组月经改善的有效率比较差异有统计学意义(P<0.05)。对照组术后复发率明显高于观察组(P<0.05)。2组不孕患者治疗后受孕情况、不良反应比较差异无统计学意义(P>0.05)。结论:宫腔镜电切术后联合服用屈螺酮炔雌醇治疗子宫内膜息肉可有效改善月经出血量和周期,降低子宫内膜息肉的复发率,且不良反应的比例低。
宫腔镜电切术;屈螺酮炔雌醇;子宫内膜息肉;疗效
doi:10.16753/j.cnki.1008-2344.2016.04.011
[Abstract]Objective:To explore the clinical efficacy of hysteroscopy combined with drospirenone ethinylestradiol in the treatment of endometrial polyps.Methods:A total of patients with endometrial polyps from Feb 2014 to Dec 2015 were randomly divided into 2 groups.The control group was given hysteroscopic surgery.Intravenous infusion of oxytocin and antibiotics after operation was done.The observation group on the basis of the control group received oral administration of drospirenone and ethinylestradiol tablets(1 tablet/d),taking 3 consecutive weeks,and a total of 3 cycles.In the postoperative 4 months follow-up,the curative effect and complications was compared.Results:There was significant difference in menstrual improvement rate in 2 groups(P<0.05).The recurrence rate in the control group was significantly higher than that in the observation group(P<0.05),but there was no difference in the pregnancy within 6 months after the surgery and adverse reactions(P>0.05).Conclusion:The endometrial polyps performed hysteroscopic surgery combined with drospirenone ethinyl estradiol can effectively improve menstrual bleeding and cycle,reduce the recurrence of endometrial polyp,and the adverse reaction.
[Key words]hysteroscopic;drospirenone ethinylestradiol;endometrial polyps;curative effect
子宫内膜息肉属于常见的妇科临床疾病,40岁左右人群发病率较高,通常会伴随着经血量增加、阴道不规律流血甚至导致不孕,对广大女性患者的身心造成严重的影响[1]。多数研究者认为,该病主要是由未成熟的子宫内膜尤其是基底部内膜部位产生,以往临床常采用常规止血、激素及刮宫等方法进行治疗但效果通常不佳[2]。随着医疗设备和技术的改进,宫腔镜下子宫内膜息肉电切术在子宫内膜息肉患者治疗中取得了良好的效果[3]。……
