肺叶袖状切除术治疗68例老年中心型肺癌效果分析
2016-08-11马震
马震

【摘要】 目的 研究肺叶袖状切除术对老年中心型肺癌的治疗效果。方法 136例老年中心型肺癌患者, 根据治疗方法不同分为观察组和对照组, 各68例。观察组患者行肺叶袖状切除术治疗;对照组患者采用全肺切除手术治疗。比较两组患者手术相关情况及远期情况。结果 观察组患者手术时间为(125.2±14.7)min、术中出血量为(463.4±46.8)ml、胸腔引流量为(452.6±64.2)ml, 均优于对照组的(156.2±10.5)min、(288.4±62.8)ml及(332.7±72.4)ml(P<0.05);观察组患者3年存活率及5年存活率分别为73.5%、55.9%, 高于对照组的54.4%、38.2%(P<0.05)。结论 治疗老年中心型肺癌时采用肺叶袖状切除术, 可缩短手术时间、减少手术出血量及引流量, 对改善患者预后、提高远期存活率有明显帮助, 值得在临床推广。
【关键词】 肺叶袖状切除术;全肺切除术;中心型肺癌
DOI:10.14163/j.cnki.11-5547/r.2016.20.019
【Abstract】 Objective To research curative effect by pulmonary lobe sleeve resection for senile central-type lung cancer. Methods A total of 136 senile central-type lung cancer patients were divided by different treatment measures into observation group and control group, with 68 cases in each group. The observation group received pulmonary lobe sleeve resection for treatment, and the control group received pneumonectomy. Comparison was made on operation condition and long-term status between the two groups. Results The observation group had all better operation time as (125.2±14.7) min, intraoperative bleeding volume as (463.4±46.8) ml and chest drainage volume as (452.6±64.2) ml than (156.2±10.5) min, (288.4±62.8) ml and (332.7±72.4) ml in the control group (P<0.05). The observation group had all higher 3-year and 5-year survival rates as 73.5% and 55.9% than 54.4% and 38.2% of the control group (P<0.05). Conclusion Implement of pulmonary lobe sleeve resection in treating senile central-type lung cancer can shorten operation time and reduce bleeding and drainage volume. This method is helpful for improving prognosis and long-term survival rate in patients, and it is worth clinical promotion.
【Key words】 Pulmonary lobe sleeve resection; Pneumonectomy; Central-type lung cancer
肺癌按生长部位分为中央型及周围型, 随着吸烟者增多、空气质量下降, 我国肺癌患者逐年增加。临床主要采用的治疗手段为手术切除原发肿瘤并清扫淋巴结。由于肺癌患者以老年人群为主, 且并发症多, 因此为降低手术对患者的影响, 在手术治疗时应充分考虑手术创伤及患者机体耐受能力[1]。本院近年来在对老年中心型肺癌患者的临床治疗中采用袖状切除术, 取得了满意的效果。现报告如下。
1 资料与方法
1. 1 一般资料 本研究通过伦理委员会批准, 选取2009年1月~2010年9月到本院诊治的136例老年中心型肺癌患者作为研究对象。所有患者经CT及纤维支气管镜检查均为中央型非小细胞肺癌[2]。根据治疗方法不同分为观察组和对照组, 各68例。对照组患者年龄63~81岁, 平均年龄(76.4±4.5)岁;
男41例, 女27例;其中鳞癌36例, 腺癌30例, 鳞腺癌2例;TNM分期Ⅰ期2例, Ⅱa期12例, Ⅱb期26例, Ⅲa期24例, Ⅲb期4例。观察组患者年龄61~79岁, 平均年龄(75.8±4.9)岁;
男46例, 女22例;其中鳞癌38例, 腺癌29例, 鳞腺癌1例;TNM分期Ⅰ期3例, Ⅱa期11例, Ⅱb期28例, Ⅲa期23例,
Ⅲb期3例。两组患者一般资料比较差异无统计学意义(P>0.05), 具有可比性。……
