不同病理类型阑尾炎阑尾直径的ROC曲线分析
2016-08-11蔡少雨韩咏峰刘珊珊古佩巧丘焰光
蔡少雨+韩咏峰+刘珊珊+古佩巧+丘焰光+陈伟娴+严冬梅


【摘要】 目的 通过回顾性对比分析不同病理类型阑尾炎的阑尾直径, 并采用受试者工作特征曲线(ROC曲线)选择诊断不同病理类型阑尾炎阑尾直径的最佳诊断界值。方法 对超声检查并得到手术及病理证实的急性单纯性阑尾炎37例、慢性阑尾炎急性发作75例、急性化脓性阑尾炎522例与坏疽性阑尾炎56例的阑尾直径进行ROC曲线分析并确定诊断不同病理类型阑尾炎阑尾直径的最佳的诊断界值。结果 采用ROC曲线确定诊断不同病理类型阑尾炎阑尾直径的最佳的诊断界值, 根据阑尾的直径界值来鉴别和判断不同病理类型阑尾炎界值如下:急性单纯性阑尾炎组对于慢性阑尾炎急性发作组(诊断界值5.20 mm)、急性化脓性阑尾炎组对于坏疽性阑尾炎组(诊断界值8.90 mm), 其诊断界值的诊断准确性均较低(AUC<0.7);急性单纯性阑尾炎组对于急性化脓性阑尾炎组(诊断界值7.95 mm)、急性单纯性阑尾炎组对于坏疽性阑尾炎组(诊断界值8.50 mm)、慢性阑尾炎急性发作组对于急性化脓性阑尾炎组(诊断界值7.25 mm)、慢性阑尾炎急性发作组对于坏疽性阑尾炎组(诊断界值7.30 mm), 其诊断界值的诊断准确性均较好(AUC>0.7)。结论 采用ROC曲线确定诊断不同病理类型阑尾炎阑尾直径的最佳的诊断界值大部分对鉴别不同病理类型的阑尾炎的诊断准确性较好。
【关键词】 阑尾炎;病理类型;超声诊断; 阑尾直径;受试者工作特征曲线
DOI:10.14163/j.cnki.11-5547/r.2016.20.001
【Abstract】 Objective To retrospectively analyze appendix diameter of appendicitis with different pathological patterns, and to determine the best diagnostic threshold value of appendix diameter for appendicitis with different pathological patterns by receiver operating characteristic (ROC) curve. Methods ROC curve analysis was made in 37 patients with acute simple appendicitis, 75 patients with acute attack of chronic appendicitis, 522 patients with acute suppurative appendicitis, and 56 patients with gangrenous appendicitis to determine the best diagnostic threshold value of appendix diameter for appendicitis with different pathological patterns. Results ROC curve was applied to identify and judge pathological pattern in accordance with appendix diameter. Diagnostic accuracy of diagnostic threshold value was low between acute simple appendicitis and acute attack of chronic appendicitis (diagnostic threshold value as 5.20 mm), acute suppurative appendicitis and gangrenous appendicitis (diagnostic threshold value as 8.90 mm) (AUC<0.7). High diagnostic accuracy of diagnostic threshold value was shown between acute simple appendicitis and acute suppurative appendicitis (diagnostic threshold value as 7.95 mm), acute simple appendicitis and gangrenous appendicitis (diagnostic threshold value as 8.50 mm), acute attack of chronic appendicitis and acute suppurative appendicitis (diagnostic threshold value as 7.25 mm), acute attack of chronic appendicitis and gangrenous appendicitis (diagnostic threshold value as 7.30 mm) (AUC>0.7). Conclusion Application of ROC curve analysis provides good accuracy in determining the best diagnostic threshold value of appendix diameter for appendicitis with different pathological patterns.
【Key words】 Appendicitis; Pathological pattern; Ultrasonic diagnosis; Appendix diameter; Receiver operating characteristic curve
普遍文献报道直径≤7 mm作为正常阑尾的标准, 典型的肿大阑尾声像图表现为最大压痛点处同心圆样、不可压缩的腊肠样结构, 直径>7 mm(也有直径>6 mm)[1]。国内文献不同病理类型阑尾炎的阑尾直径报道不一[2-14], 超声检查中无论哪一节段阑尾横切面直径>6 mm, 压缩性不明显, 回声减低, 即提示有阑尾节段性肿大, 借此可做出阑尾炎诊断[15, 16]。基于以……
