APP下载

干扰素联合微波治疗宫颈糜烂合并HPV感染的效果分析

2016-07-05温展翀徐干如

中国实用医药 2016年13期

温展翀 徐干如

【摘要】 目的 观察分析干扰素联合微波治疗宫颈糜烂合并人乳头瘤病毒(HPV)感染的临床效果。方法 132例宫颈糜烂合并HPV感染患者, 按照随机数字表法分为观察组和对照组, 每组66例。对照组采用微波治疗, 观察组在对照组的基础上联合干扰素治疗。比较两组患者的临床效果, 对治疗总有效的患者进行1年随访, 比较两组6个月及1年复发率。结果 观察组重度患者治疗总有效率85.71%显著高于对照组的57.14%(P<0.05);观察组6个月及1年复发率分别为4.84%和9.68%, 明显低于对照组的20.00%和32.73%(P<0.05)。结论 干扰素联合微波治疗宫颈糜烂合并HPV感染, 疗效显著, 复发率

低, 值得临床大力推广并应用。

【关键词】 干扰素;微波;宫颈糜烂;人乳头瘤病毒感染

DOI:10.14163/j.cnki.11-5547/r.2016.13.006

Analysis of effect by interferon combined with microwave in the treatment of cervical erosion complicated with HPV infection WEN Zhan-chong, XU Gan-ru. Department of Obstetrics and Gynecology, Shenzhen Yantian District Peoples Hospital, Shenzhen 518083, China

【Abstract】 Objective To observe and analyze clinical effect by interferon combined with microwave in the treatment of cervical erosion complicated with human papilloma virus (HPV) infection. Methods A total of 132 cervical erosion complicated with HPV infection patients were divided by random number table into observation group and control group, with 66 cases in each group. The control group received microwave for treatment, and the observation group received additional combination of interferon for treatment. Comparison was made on clinical effects between the two groups. Effective patients in treatment received follow-up for 1 year, and recurrence rates in 6 months and 1 year were compared. Results The observation group had much higher total effective rate as 85.71% than 57.14% of the control group (P<0.05). Recurrence rates in 6 months and 1 year were 4.84% and 9.68% in the observation group, and those were much lower than 20.00% and 32.73% in the control group (P<0.05). Conclusion Combination of interferon and microwave shows precise effect and low recurrence rate in treating cervical erosion complicated with HPV infection. It is worth widely clinical promotion and application.

【Key words】 Interferon; Microwave; Cervical erosion; Human papilloma virus infection

宫颈糜烂是妇科常见疾病的一种, 主要临床症状为白带淡黄色、脓性、出血等, 甚至不孕, 严重影响了患者的生活质量[1]。临床治疗宫颈糜烂的方法较多, 常见的有药物治疗、物理治疗及手术治疗等, 均无法根治、复发率高, 临床疗效较差。有研究发现[2, 3], 引起宫颈糜烂的主要原因之一是HPV感染。作者通过对66例宫颈糜烂合并HPV感染患者采用微波联合重组人干扰素α-2b泡腾胶囊治疗, 并将临床效果与同期仅采用微波治疗的患者进行比较, 疗效较满意, 现报告如下。

1 资料与方法

1. 1 一般资料 选择本院2013年8月~2014年8月收治的132例宫颈糜烂合并HPV感染患者, 均经妇科及阴道清洁度检查, 符合乐杰主编的《妇产科学》中规定的HPV感染宫颈糜烂诊断标准, 同时排除生殖道急性炎症、宫颈癌患者, 妊娠及哺乳期妇女。年龄28~53岁, 平均年龄(42.1±4.2)岁, 病程0.6~4.0年, 平均病程(2.1±0.4)年, 轻度34例, 中度56例, 重度42例;单纯型32例, 颗粒型66例, 乳突型34例;……

登录APP查看全文