危重症哮喘的临床诊断和治疗效果探讨
2016-02-27邓小彬许子涛
邓小彬+许子涛


[摘要] 目的 通过对呼吸内科重症哮喘的临床诊断、分析与探讨,确定治疗方案的治疗效果。 方法 选取2015年1~3月我院收治的入住呼吸内科病房的180例病例作为研究对象(观察组),同时选取文献资料的260例常规治疗患者的资料作为对照组。本研究采用联合治疗的内容包括氨茶碱静脉滴注,盐酸肾上腺注射液滴注,溴化异丙托品气雾剂吸入,地塞米松静脉滴注,以及一系列的抗感染、抗代谢紊乱、通气平衡等辅助治疗。对比治疗前后患者的心率、呼吸频率、pH、PaO2、PaCO2、PIP、Pplant等评价指标。 结果 治疗后观察组患者的心率、呼吸频率、PaCO2值等较治疗前均有显著下降,而血气分析结果、PIP值、Pplant值、MV等均有显著升高,差异具有统计学意义(P<0.05)。观察组治疗有效率为95.6%,与对照组的81.5%比较,差异有统计学意义(P<0.05)。 结论 在重症哮喘治疗中,茶碱类药物、糖皮质激素、β受体激动剂以及机械通气等效果十分明显,可以进行更大范围的推广。
[关键词] 危重症哮喘;糖皮质激素;氨茶碱;β-受体激动剂;血气分析
[中图分类号] R562.25 [文献标识码] B [文章编号] 1673-9701(2015)26-0034-03
Exploration of clinical diagnosis and treatment effect of severe asthma
DENG Xiaobin XU Zitao
Second Department of Internal Medicine, Hospital of Thirteenth Engineering Bureau of China Water Resources and Hydropower, Dezhou 253000, China
[Abstract] Objective To determine the treatment effects of treatment programs through the clinical diagnosis, analysis and investigation of severe asthma in the respiration medicine department. Methods A total of 180 patients treated and hospitalized in the respiration medicine department of our hospital from January to March of 2015 were selected as the study subjects (observation group) and meanwhile clinical data of 260 patients who received conventional treatment were selected as the control group. Combined treatment was used in this study, including intravenous drip of aminophylline, intravenous drip of adrenaline hydrochloride injection, aerosol inhalation of ipratropium bromide, intravenous drip of dexamethasone and a series of adjuvant therapy such as anti-infection, anti-metabolic disorder and ventilation balance. Evaluation indicators such as heart rate, respiratory rate, pH, PaO2, PaCO2, PIP and Pplant of the patients before and after the treatment were analyzed. Results After the treatment, the observation group patients heart rates, respiratory rates and PaCO2 decreased significantly, but the blood gas analysis results, PIP values, Pplant values and MV increased significantly, with statistically significant differences(P<0.05). The treatment of efficient of observation group was 95.6%, comparing with 81.5% of the control group, the difference was statistically significant(P<0.05). Conclusion In the treatment of severe asthma, theophyllines, glucocorticoids, β receptor agonists and mechanical ventilation all show obvious effects and can be promoted in a wider range.
[Key words] Severe asthma; Glucocorticoids; Aminophylline; β-receptor agonist; Blood gas analysis
危重哮喘是呼吸内科一种较为严重且临床常见的疾病,患者多以呼吸困难、语言功能障碍为主要症状[1]。目前临床水平对此病的治疗并不能达到理想效果[2]。因此对危重哮喘病症诊断与治疗若不及时,可直接威胁到患者的健康和生命安全[3]。本研究通过对180例危重哮喘患者在联合治疗方案下治疗的临床疗效进行研究,取得了较好的效果,现报道如下。
1 资料与方法
1.1 一般资料
选择2015年1~3月我院收治的危重哮喘住院患者180例作为研究对象(观察组),其中男108例(60.0%),女72例(40.0%),平均年龄(59.8±10.6)岁,病程0.5~20.5年,平均(9.98±3.73)年。选取资料记载的传统治疗案例中危重哮喘患者共260例为对照组,其中男159例(61.2%),女101例(38.8%),平均年龄(58.6±9.7)岁,病程0.5~20.5年,平均(10.20±3.42)年。……
