牟建明吉林省吉林市第六人民医院早期干预疗区，吉林吉林　132001

住院精神分裂症患者用药管理安全性的调查研究

牟建明
吉林省吉林市第六人民医院早期干预疗区，吉林吉林132001

目的 研究住院精神分裂症患者的用药管理安全性。方法 分析住院精神分裂症患者的用药及安全性，得出住院精神分裂症患者用药管理的注意事项。结果 住院精神分裂症患者的用药方法有单一药物治疗和联合用药两种。其中单一药物治疗包括利培酮、阿立哌唑、氯氮平、盐酸苯海索、舒必利、富马酸奎硫平、氯丙嗪。联合用药包括两联用药和三联用药。男性患者主要应用氯氮平、舒必利、氯丙嗪、富马酸奎硫平等疗效较为迅速的药物，女性患者多应用利培酮等对内分泌影响较小的药物进行治疗。结论 正常情况下，应尽量采取单一治疗方法。只有当患者情况较为严重，单一药物不能达到治疗效果时，才可考虑采取联合治疗。在药物治疗达到效果后，不能突然停药，以防止病情复发。

住院；精神分裂；用药管理；安全性

［Abstract］Objective To research the medication management safety of inpatients with schizophrenia.Methods The medication and safety of inpatients with schizophrenia were analyzed and the notes of medication management in inpatients with schizophrenia were obtained.Results The medication methods of inpatients with schizophrenia included the single-drug treatment and combined medication，among them，the single-drug treatment included risperidone，aripiprazole，clozapine，paralest，sulpiride，quetiapine fumarate and chlorpromazine，the combined medication included two-drug medication and three-drug medication，the male patients mainly used the drugs with rapid curative effect such as clozapine，sulpiride，chlorpromazine and quetiapine fumarate，and the female patients mostly used the drugs with less effect on endocrine secretion such as risperidone for treatment.Conclusion Normally，we should try to adopt the single treatment method，only when the patient's disease condition is serious and the single drug fails to obtain the treatment effect，can we consider the combined treatment，and we can't stop drug administration suddenly in order to prevent the recurrence of disease condition after the drug treatment achieves the effect.

［Key words］Hospitalization；Schizophrenia；Medication management；Safety

现今，随着生活节奏的加快及生活压力的加大，精神分裂症的发生率也在逐年增加。有的精神分裂症患者出现躁狂、抑郁等不同形式的精神疾病，严重者甚至丧失了劳动能力。给患者及家人、甚至邻居都造成一定的伤害［1-7］。目前，针对精神分裂疾病的治疗还没有根治的方法，多数患者都是靠长期用药来控制病情，一旦出现断药或强烈的外界刺激，就会有复发的可能。……