戴君君 张美英 王春兰 方英 潘祯 潘敏芳

[摘要] 目的 探讨温灸包热熨在预防宫颈癌同步放化疗患者放射性直肠炎中临床效果。 方法 选取2014年12月～2015年3月60例Ⅱb～Ⅳa期宫颈癌同步放化疗患者，随机分为对照组与观察组，各30例。观察组患者在同步放化疗期间同时进行神阙穴温灸包热熨治疗，每日1次，至治疗结束；对照组在同步放化疗期间不应用温灸包热熨，观察两组患者放射性直肠炎的发生情况。 结果 观察组放射性直肠炎的发生率低于对照组，发生时间较对照组迟，发生3 级以上直肠炎的患者明显少于对照组，差异有统计学意义（P<0.05）。 结论 温灸包热熨能降低放射性直肠炎的发生率，减轻直肠的放射性损伤 。

[关键词] 温灸包；宫颈癌；同步放化疗；放射性直肠炎

[中图分类号] R737.3 [文献标识码] B [文章编号] 1673-9701（2015）34-0067-04

Clinical observation of effect of warm moxibustion heat in treatment of preventing radiation proctitis on concurrent chemoradiotherapy patients

DAI Junjun ZHANG Meiying WANG Chunlan FANG Ying PAN Zhen PAN Minfang

Department of Gynecological Radiotherapy， Zhejiang Cancer Hospital， Hangzhou 310022， China

[Abstract] Objective To investigate the clinical effect of warm moxibustion heat at preventing radiation proctitis for the patients with cervical cancer who were given concurrent chemoradiotherapy. Methods All 60 cases of Ⅱb-Ⅳa patients were studied from December 2014 to March 2015 for concurrent chemoradiotherapy warm moxibustion treatment， they were divided into observation group and control group， each of 30 cases. The observation group used Shenque Acupoint treatment combined with concurrent chemoradiotherapy， one time per day till end of treatment， while the control group was only given concurrent chemoradiotherapy for treatment， the occurrence of radiation proctitis in two groups were observed and compared. Results The incidence of radiation proctitis was lower in observation group than control group， so did the occurring time， the patients in observation group who had above 3r grade proctitis were significantly less than control group， the difference was statistically significant（P<0.05）. Conclusion Warm moxibustion heat can lower the incidence of low radiation proctitis， ease the harm of radiation on rectum.

[Key words] Warm moxibustion heat； Cervical cancer； Concurrent chemoradiotherapy； Radiation proctitis

宫颈癌是发展中国家妇女最常见的恶性肿瘤，而我国是宫颈癌的高发地区，是世界上患者数最多的国家[1]。同步放化疗是目前治疗宫颈癌的首选方法[2]。放射性直肠炎是放疗过程中常见的并发症，其发病率随放疗技术的广泛应用而逐渐增高[3]，临床症状为排便次数增多、腹部疼痛、腹泻、里急后重、黏液血便，直肠瘘或穿孔，严重时可使患者难以坚持治疗，从而影响治疗效果给患者生活造成很大的不便和痛苦。但仍缺乏有效的治疗手段。因此，急需寻找一种方便有效、安全无不良反应的放射性直肠炎的辅助疗法，是临床治疗工作中亟待解决的问题之一。 目前国内外尚无利用温灸包热熨干预放射性直肠炎的相关研究，我科于2014年12月～2015年3月FP方案同步化疗的宫颈癌患者采用神阙穴温灸包热熨预防放射性直肠炎，疗效较好，现报道如下。……