依托考昔与塞来昔布治疗急性痛风的疗效与安全性

夏红梅

吉林省吉林市中心医院药剂科，吉林吉林132000

[摘要]目的探讨依托考昔与塞来昔布治疗急性痛风的疗效与安全性。方法随机选取该院2013年4月—2014年6月收治的80例急性通风患者，并将其随机分为实验组与对照组，各40例。其中实验组患者采用依托考昔进行口服治疗；对照组患者采用塞来昔布进行口服治疗。对比两组通风患者的各项数据。结果两组急性痛风患者进行治疗后发现，实验组患者的其他各项指标均优于对照组患者。两组急性痛风患者治疗后的VAS评分存在明显差异，P＜0.05，差异有统计学意义。结论依托考昔能够有效的对急性痛风患者进行治疗，具有安全性高、起效快等优点，值得临床推广使用。

[关键词]依托考昔；塞来昔布；急性痛风

[中图分类号]R4

[文献标识码]A

[文章编号]1674-0742（2015）10（a）－0156-02

[作者简介]夏红梅（1971.9－）,女,吉林省吉林市人，本科，副主任药师，研究方向：药物的临床应用。

Abstract[]Objective To investigate the efficacy and safety of etoricoxib and celecoxib in the treatment of acute gout.Methods 80 cases of acute ventilation were selected from April 2013 to June 2014, and were randomly divided into experimental group and control group, 40 cases in each group.In the experimental group were treated with etoricoxib oral treatment; the control group were treated with celecoxib oral treatment.Compare the data of two groups of ventilation patients.Results Two groups of patients with acute gout were treated, the other indicators of the experimental group were better than those of the control group.There were sig鄄nificant differences in VAS score between the two groups after treatment, P<0.05, the difference was statistically significant.Con鄄clusion Relying on past exam can effectively in patients with acute gout treatment, which has the advantages of high safety, fast action and so on, worthy of clinical use.

收稿日期：（2015-07-09）

The Efficacy and Safety of Etoricoxib and Celecoxib in the Treatment of Acute Gout

XIA Hong-mei

Department of Pharmacy, Jilin Central Hospital, Jilin, Jilin Province, 132000 China

[Key words]Etoricoxib; Celecoxib; Acute gout

引起痛风的主要因素在于嘌呤代谢紊乱以及尿酸排泄量降低而导致的，高尿酸血症以及反复发作的关节炎使其主要的临床表现症状[1]。传统的非甾体类抗炎药会导致胃肠道出现一系列的不良反应，特别是老年人，其耐受性会降低[2]。该研究随机选取该院2013年4月—2014年6月收治的80例急性痛风患者，研究阐述了两种非甾体类抗炎药对急性痛风患者进行治疗，并将其各项指标进行对比，现报道如下。

1　资料与方法

1.1一般资料

随机选取收治的80例急性痛风患者，并对其进行随机分组，各40例。……