子宫前壁肌层厚度与早产的关联性研究

任慧，韩笑，贾赛玉

常州市妇幼保健院超声科，江苏常州213003

[摘要]目的探讨子宫前壁肌层厚度与早产发生的关联。方法于2010年1月—2014年12月在该院产检的孕20~28周产妇行三维彩色超声仪测量孕20~28周孕妇的子宫前壁肌层厚度，分析其与早产发生的相关性。结果研究最终纳入855例孕妇，其中早产组118例，足月组737例。早产组孕中期子宫前壁肌层厚度为(5.57±0.78) mm，足月组为(5.36±2.12) mm，两组差异无统计学意义(P=0.29＞0.05)。在有胎膜早破中，早产组的子宫前壁肌层厚度为(5.77±0.81) mm，较足月(5.20±1.15) mm显著增厚，两组比较差异有统计学意义(P<0.05)。结论妊娠中期子宫前壁肌层厚度与自发性早产和胎膜早破早产均存在关联，但子宫前壁肌层厚度可能不是早产的独立影响因素。

[关键词]子宫前壁肌层厚度；早产；超声检测

[中图分类号]R7

[文献标识码]A

[文章编号]1674-0742（2015）10（a）－0064-03

[作者简介]任慧（1978-），女，江苏淮安人，本科，主治医师，研究方向：妇产科超声方向。

Abstract[]Objective To investigate the relationship between the anteriormyometrial (MA) thickness and preterm delivery by ultrasound.Methods Some pregnant women underwent prenatal examination in this hospital between January 2010 and December 2014 at 20-28 gestational weeks, and we measured the MA thickness using 3D-color ultrasonic instrument and analyzed its relationship with preterm delivery.Results A total number of 855 pregnant women were enrolled in this study, in which 118 were assigned to preterm delivery group and 737 to full term group.The MA thickness was 5.57±0.78 mm in the preterm delivery group and 5.36±2.12 mm in the full term group, and there was no statistically significant difference between them, (P=0.29).Among those who experienced premature rupture of membranes, the MA thickness was 5.77±0.81mm in the preterm delivery group, significantly higher than that, 5.20±1.15 mm, in the full term group, and the difference was statistically significant, P<0.05.Conclusion Midterm MA thickness is correlated with spontaneous preterm delivery and that caused by premature rupture of membranes, but may not be an independent factor.

收稿日期：（2015-07-05） （2015-07-04）

Relationship Between the Anteriormyometrial Thickness and Preterm Delivery

REN Hui，HAN Xiao，JIA Sai-yu

Department of Ultrasound, Changzhou Maternity and Child Health Care Hospital affiliated to Nanjing Medical University, Changzhou, Jiangsu Province, 213003 China

[Key words]Anteriormyometrial thickness; Preterm delivery; Ultrasound

早产是指在妊娠28~37周间分娩者，是常见的妊娠并发症之一[1]。我国早产儿出生率已超过5.99%，其死亡率为12.7%~ 20.8%,占婴儿死亡总数的60%~70%[2]。早产给围产儿的预后及生存带来了诸多不良结局[3]。早产常见原因有感染、胎膜早破、子宫过度膨胀、子宫颈口关闭不全等。Atarjavdan等[4]研究孕妇子宫肌层厚度与胎膜早破关联时发现，胎膜未破的早产孕妇子宫肌层较胎膜早破早产孕妇薄。另外Sokolowski等[5]研究认为，早产孕妇的子宫肌层厚度较足月产孕妇增厚。因此，关于孕妇子宫肌层厚度与早产的相关性还存在争议，该研究者通过检测2010年1月—2014年12月在该院产检的孕20~28周产妇子宫前壁肌层厚度，前瞻性的探讨子宫肌层厚度与早产发生的关联，现报道如下。……