重症胰腺炎应用连续性肾脏替代治疗的效果分析

仲伦

厦门大学附属中山医院重症医学科，福建厦门361004

[摘要]目的分析并探讨重症胰腺炎应用连续性肾脏替代治疗的效果，为胰腺炎的救治提供一定的理论依据。方法随机选取该院2014年1—12月收治的80例重症胰腺炎患者为研究对象，根据治疗方法的不同将其平均分为观察组和对照组，每组40例患者。对照组患者采取常规治疗方法，观察组患者在常规治疗基础上应用连续性肾脏替代治疗方法，比较治疗前后患者的生命体征及肾功能变化情况。结果应用连续性肾脏替代疗法后，患者的腹痛腹胀症状得以缓解，血压、心率以及呼吸次数指标正常，与对照组相比在治疗前后差异有统计学意义（P＜0.05）。结论针对重症胰腺炎患者应用连续性肾脏替代疗法，有利于控制患者的病情，提升其存活率，对促进患者的预后康复具有显著的临床意义，值得在今后的治疗护理中推广应用。

[关键词]重症胰腺炎；连续性肾脏替代疗法：效果

[中图分类号]R59

[文献标识码]A

[文章编号]1674-0742（2015）10（a）－0045-03

[作者简介]仲伦(1977.8-)，男，江苏连云港人，硕士，主治医师，研究方向：重症医学。

Abstract[]Objective To analyze and investigate the effect of continuous renal replacement therapy on severe acute pancreatitis so as to provide a theoretical basis for the treatment of pancreatitis.Methods 80 cases with severe acute pancreatitis admitted in our hospital from January 2014 to December 2014 were selected as the subjects and equally divided into the observation group and the control group with 40 cases in each in accordance with the treatment given to them.Both groups were treated by the conventional method, the observation group was additionally treated by continuous renal replacement therapy.And the vital signs and renal function were compared between the two groups before and after treatment.Results Compared with the control group, in the observation group after treated by continuous renal replacement therapy, the abdominal pain and distension alleviated, blood pressure, heart rate and breathing frequency were normal, the difference between the two groups before and after treatment was statistically significant (P<0.05).Conclusion For patients with severe acute pancreatitis, continuous renal replacement therapy is of great clinical significance in controlling the conditions, increasing the survival rate, and improving the prognosis and rehabilitation, so it is worthy of popularization and application in the treatment and nursing in the future.

收稿日期：（2015-06-22）（ 2015-06-27）

The Effect of Continuous Renal Replacement Therapy on Severe Acute Pancreatitis

ZHONG Lun

Intensive Care Unit, Zhongshan Hospital Xiamen University, Xiamen, Fujian Province, 361004 China

[Key words]Severe acute pancreatitis; Continuous renal replacement therapy; Effect

重症胰腺炎是急腹症的一种，凭借其起病急、发病重、并发症多等特点成为了威胁患者生命健康的头号杀手。重症胰腺炎的致死率很高，根据2013年中国急性胰腺炎诊治指南，重症胰腺炎的病死率较高，为36%~50%，如后期合并感染则病死率极高。为了改善重症胰腺炎患者的生命健康质量，目前临床中应用连续性肾脏替代治疗方法，其是指持续利用血液净化技术清除溶质，以替代受损肾功能以及对脏器功能起保护支持作用的治疗方法。……