慢性咽喉炎病因分析
2015-10-16孙文青
孙文青

[摘要] 目的 探索慢性咽喉炎的病因及治疗方法。 方法 将2013年5—12月确诊为慢性咽喉炎的60名患者随机分为两组,治疗组采用泮托拉唑钠肠溶胶囊,对照组采用芩连胶囊口服治疗2周,观察两组的临床疗效。 结果 泮托拉唑钠肠溶胶囊治疗组的有效率96.67%,对照组的有效率56.67%,经χ2检验,差异有统计学意义(P<0.05)。 结论 治疗组的症状与体征改善明显高于对照组,证明反流性因素在慢性咽喉炎患者中普遍存在,间接证实慢性咽喉炎的主要致病因素可能是消化液反流。
[关键词] 慢性咽喉炎; 病因 ;反流性
[中图分类号] R195 [文献标识码] A [文章编号] 1674-0742(2015)09(a)-0028-02
Analysis of the Causes of Chronic Pharyngitis
SUN Wen-qing
Otolaryngology head and neck surgery,The Second Hospital Affiliated of Henan University of Science and Technology, Luoyang, Henan Province, 471000 China
[Abstract] Objective To explore the etiology and treatment of chronic pharyngitis. Methods May 2013 - December 2013 diagnosed as chronic inflammation of the throat of the 60 patients were randomly divided into to two groups, treatment group with pantoprazole sodium enteric coated capsule and control group with Qinlian capsules orally for 2 weeks were observed the clinical efficacy of the two groups. Results Pantoprazole sodium enteric coated capsules in the treatment group, the effective rate of 96.67%, the control group with effectiveness 56.67%, by chi square test, the difference is statistically significant (P < 0.05). Conclusion The symptoms and signs of improvement in the treatment group was significantly higher than the control group, proving that the flow factors exist in patients with chronic pharyngitis, chronic pharyngitis indirectly confirmed the main pathogenic factors may be digestive fluid reflux.
[Key words] Chronic pharyngitis; Etiology; Reflux
慢性咽喉炎是指咽喉部黏膜、黏膜下及淋巴组织的慢性炎症,是耳鼻咽喉科的常见疾病,不少患者咽喉部症状长期存在,严重影响生活质量,但因其无严重的后果或并发症,常常受到临床医师的忽视,缺少严谨的临床研究结果,治疗上多建议戒烟酒,少辛辣,使用清热解毒的中成药甚至抗生素等治疗,疗效参差不齐。近些年来,已经有研究者关注到胃酸返流的因素在慢性咽喉炎致病中占据一定比例,有资料发现慢性咽喉炎病人中,有4%~10%与咽喉反流有关[1],为进一步探索慢性的病因治疗,该研究将整群选取该院2013年5月—2013年12月确诊为慢性咽喉炎的60名患者随机分为两组,治疗组采用泮托拉唑钠肠溶胶囊,对照组采用芩连胶囊口服治疗2周,现报道如下。
1 资料与方法
1.1 一般资料
1.1.1 纳入标准 ①年龄18~60岁;②症状为咽喉部不适感、异物感或频频清嗓,伴或不伴有咳白色粘痰;③电子喉镜检查咽喉部慢性充血或水肿,伴有或不伴有舌根扁桃体增生、会厌黏膜小囊肿、声带肥厚;④病程大于3月。
1.1.2 排除标准 ①急性、慢性鼻窦炎患者;……
