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不同血液检验指标在冠心病患者中的诊断价值

2015-09-11刘建国

中国当代医药 2015年24期
关键词:临床应用冠心病

刘建国

[摘要] 目的 研究探讨不同血液检验指标在冠心病患者中的应用价值。 方法 选取2013年4月~2014年12月我院收治的冠心病患者110例作为研究对象,将其作为观察组,回顾性分析患者的基本临床资料,记录患者的红细胞分布宽度(RDW)、血小板计数(PLT)、血小板分布宽度(PDW)、血小板压积(PCT)与平均体积(MPV)、心肌肌钙蛋白I(cTnI)水平、心肌肌钙蛋白T(cTnT)水平及高敏心肌肌钙蛋白T(hs-cTnT)水平、血液中的肌酸激酶同工酶(CK-MB)值、血清同型半胱氨酸(Hcy)水平等多项血液检测指标。选择同期在医院接受体检的健康志愿者100例作为对照,比较两组患者各项血液检测指标之间的差异。 结果 观察组患者的RDW、cTn、CK-MB、Hcy等指标均显著高于对照组,差异有统计学意义(P<0.05);两组血小板相关指标比较,差异无统计学意义(P>0.05)。 结论 冠心病患者的多项血液指标与病理变化有密切联系,可作为冠心病患者的诊断依据,尤其是RDW的检测,既能对患者心肌损伤的情况进行诊断,还可预测患者的预后,值得临床推广应用。

[关键词] 血液检验指标;冠心病;临床应用

[中图分类号] R446.11 [文献标识码] A [文章编号] 1674-4721(2015)08(c)-0135-03

[Abstract] Objective To study the application value of different blood test indicators detected in patients with coronary heart disease. Methods One hundred and ten patients with coronary heart disease admitted into our hospital from April 2013 to December 2014 were selected as research objects and classified into observation group.The basic clinical data was retrospectively analyzed.Many blood test indicators including red blood cell distribution width(RDW),platelet count(PLT),platelet distribution width(PDW),thrombocytocrit(PCT) and mean volume(MPV),cardiac troponin I(cTnI) level, cardiac troponin T(cTnT) level,high-sensitivity cardiac troponin T (hs-cTnT)level, blood creatine kinase (CK-MB) value,and serum homocysteine(Hcy) level were recorded.Another group of 100 healthy volunteers for physical examinations in our hospital during the same period were categorized into control group.The difference of each blood test indicator between two groups was compared respectively. Results The RDW,cTn,CK-MB and Hcy in observation group was much higher than that in control group respectively,with statistical differences(P<0.05).There was no statistical difference in platelet-related indicators between two groups(P>0.05). Conclusion Many items of blood test indicators in coronary heart disease patients are closely related with their pathological changes,and can be considered as diagnostic basis for coronary heart disease patients,especially RDW,which makes a diagnosis of patient′s myocardial injury and also predicts a prognosis,and is worthy of clinical application and promotion.

[Key words] Blood test indicator;Coronary heart disease;Clinical application

冠心病是临床常见心血管疾病,随着患者年龄的增大,其发病率呈显著上升趋势[1]。冠心病的发生和发展被认为是多种因素共同作用的结果,不同血液检验指标对冠心病病情判断和预后改善具有重要价值,其病理、生理发展过程跟血小板和红细胞相关参数具有密切联系,为探讨不同血液检验指标对冠心病患者的诊断价值,本文就我院收治的冠心病患者作为研究对象进行研究。

1 资料与方法

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