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磁疗联合动机性访谈治疗酒依赖伴焦虑抑郁的临床研究

2015-08-18韦强等

中国医药导报 2015年14期
关键词:抑郁焦虑

韦强等

[摘要] 目的 探讨磁疗联合动机性访谈治疗酒依赖伴焦虑抑郁患者的效果。 方法 选择2014年1月~2015年1月广西壮族自治区脑科医院诊治的酒依赖伴焦虑抑郁患者60例,随机分为研究组(30例)和对照组(30例),研究组采用磁疗联合动机性访谈治疗,对照组单用动机性访谈治疗。采用酒依赖戒断综合征评定表(AWS)、Zung焦虑自评量表(SAS)、Zung抑郁自评量表(SDS),对治疗前及治疗后2、4、6周相关得分进行评定,分析两组的治疗效果。 结果 与治疗前比较,对照组4、6周后AWS、SAS、SDS评分显著降低,差异有统计学意义(P < 0.05或P < 0.01);研究组治疗2、4、6周后AWS、SAS、SDS评分显著降低,差异有统计学意义(P < 0.05或P < 0.01)。治疗2、4、6周后,研究组AWS、SAS、SDS评分均明显低于对照组,差异均有统计学意义[治疗2周后:(4.4±1.2)、(63.5±14.0)、(70.4±10.3)比(5.4±1.2)、(71.38±12.1)、(73.5±9.5)分,t = 7.250、9.004、8.964,P < 0.05;治疗4周后:(2.2±0.3)、(54.1±8.3)、(60.3±8.4)比(3.8±0.8)、(65.4±9.2)、(67.9±10.8)分,t = 11.596、11.207、12.448,P < 0.01;治疗6周后:(0.7±0.1)、(42.3±10.0)、(51.1±11.3)比(1.3±0.2)、(46.9±9.2)、(61.4±10.9)分,t = 14.003、13.557、14.115,P < 0.01],尤以4、6周更为明显。两组AWS、SAS、SDS评分减分率比较,研究组[(90.0±0.9)%、(45.1±1.2)%、(36.4±0.1)%]均明显高于对照组[(80.3±1.1)%、(38.7±1.2)%、(24.0±1.5)%],差异均有统计学意义(t = 8.015、9.332、8.775,P < 0.05)。 结论 磁疗联合动机性访谈治疗酒依赖伴焦虑抑郁患者效果优于单用动机性访谈,可为临床医生对酒依赖伴焦虑抑郁的治疗提供有效的参考。

[关键词] 磁疗;动机性访谈;酒依赖;焦虑;抑郁

[中图分类号] R749.6 [文献标识码] A [文章编号] 1673-7210(2015)05(b)-0053-04

Control study of magnetic therapy combined motivated interview in the treatment of alcohol dependence with anxiety and depression

WEI Qiang LI Jie LI Rongyu CHEN Qiang YANG Cheng PAN Runde

Brain Hospital of Guangxi Zhuang Autonomous Region, Guangxi Zhuang Autonomous Region, Liuzhou 545005, China

[Abstract] Objective To study the effect of magnetic therapy joint motivated interview in the treatment of alcohol dependence with anxiety and depression. Methods From January 2014 to January 2015, in Brain Hospital of Guangxi Zhuang Autonomous Region, 60 patients with alcohol dependence with anxiety and depression were selected and randomly divided into the research group (n = 30) and the control group (n = 30), the research group was given magnetic therapy combined with motivated interview treatment, the control group was given motivated interview treatment alone. The alcohol dependence withdrawal syndrome evaluation form (AWS), self-evaluation of Zung's anxiety scale (SAS), Zung's depression self rating scale (SDS) were used to assess the relevant scores before the treatment and after the treatment 2, 4, 6 weeks, and the therapeutic effect of two groups were analyzed. Results Compared with before the treatment, the AWS, SAS, SDS scores in the control group after the treatment 4, 6 weeks decreased significantly, the differences were statistical significance (P < 0.05 or P < 0.01); the AWS, SAS, SDS scores in the research group after the treatment 2, 4, 6 weeks decreased significantly, the differences were statistical significance (P < 0.05 or P < 0.01). After treatment 2, 4, 6 weeks, the AWS, SAS, SDS scores in research group were significantly lower than those in the control group, the differences were statistically significant [after treatment 2 weeks: (4.4±1.2), (63.5±14.0), (70.4±10.3) vs (5.4±1.2), (71.38±12.1), (73.5±9.5) scores, t = 7.250, 9.004, 8.964, P < 0.05; after treatment 4 weeks: (2.2±0.3), (54.1±8.3), (60.3±8.4) vs (3.8±0.8), (65.4±9.2), (67.9±10.8) scores, t = 11.596, 11.207, 12.448, P < 0.01; after treatment 6 weeks: (0.7±0.1), (42.3±10.0), (51.1±11.3) vs (1.3±0.2), (46.9±9.2), (61.4±10.9) scores, t = 14.003, 13.557, 14.115, P < 0.01], especially in 4, 6 weeks showed more obvious. The points rate comparison in two groups of AWS, SAS, SDS scores, these in the research group [(90.0±0.9)%, (45.1±1.2)%, (36.4±0.1)%] were significantly higher than those in the control group [(80.3±1.1)%, (38.7±1.2)%, (24.0±1.5)%], the differences were statistically significant (t=8.015, 9.332, 8.775, P < 0.05). Conclusion Magnetic therapy comleined motivated interview in the treatment of alcohol dependence with anxiety and depression is better than using motivated interview alone, it can provide effective reference for the clinical doctors for the treatment of alcohol dependence with anxiety and depression.

[Key words] Magnetic therapy; Motivated interview; Alcohol dependence; Anxiety; Depression

在当今世界饮酒作为一种生活习惯和社会风俗,成为各国的公共卫生问题。调查显示84%男性和25%女性有过饮酒行为,其中16%男性和2.5%女性每晚饮酒[1]。酒精的有害性使用在全球都是对健康危害最为严重的问题之一[2-4]。酒后驾车导致交通事故也是当今社会严重问题之一[5]。提倡不饮酒或少饮酒,对酒依赖患者进行有效治疗,是摆在我们医务工作者面前的一个重要的课题[6]。

近几年来,国内对酒依赖伴焦虑抑郁的治疗方法很多。药物起效快,更有利于控制病情,特别急性发作、中重度患者。但药物治疗中仍存在诸多问题,临床上常用抗焦虑抑郁药,由于长期使用,必然对患者躯体造成损害,出现一些药物不良反应,安全性差,降低患者的依从性,不能有效降低复发率。在酒依赖伴焦虑抑郁的治疗中,心理治疗是基础,但单用心理治疗,对急性发作、中重度患者,效果不明显。……

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