新生儿重症监护病房医院感染高危因素分析
2015-03-13都美玲杨琳牟飞飞
都美玲 杨琳 牟飞飞
[摘要] 目的 探讨新生儿重症监护病房医院感染的高危因素。 方法 分析2013年5月~2014年8月滨州医学院烟台附属医院新生儿重症监护室收治的1650例患儿的临床资料。根据是否发生医院感染进行临床分组,医院感染组150例和非感染组1500例。观察两组小于胎龄儿、出生体重≤1500 g、胎龄≤37周、羊水污染、新生儿窒息、肠外营养、机械通气情况。采用多因素Logistic回归分析新生儿重症监护病房医院感染的高危因素。 结果 两组新生儿出生体重≤1500 g、胎龄≤37周、新生儿窒息、肠外营养、机械通气差异均有统计学意义(均P < 0.05);多因素Logistic回归分析,出生体重≤1500 g、胎龄≤37 周、新生儿窒息、肠外营养、机械通气均是新生儿重症监护病房医院感染高危因素(OR=1.818、4.468、4.049、4.897、3.768,P < 0.05)。 结论 及时规避新生儿重症监护病房医院感染高危因素,对于预防新生儿重症监护病房医院感染具有重要的意义。
[关键词] 新生儿重症监护病房;医院感染;高危因素
[中图分类号] R722 [文献标识码] A [文章编号] 1673-7210(2015)02(b)-0048-04
[Abstract] Objective To approach high risk factors of hospital infection in Neonatal Intensive Care Unit (NICU). Methods Clinical data of 1650 cases of newborn from May 2013 to August 2014 in NICU of Yantai Affiliated Hospital of Binzhou Medical University were analyzed. According to whether the hospital infection in clinical, they were divided into two groups, hospital infection group 150 cases and non-hospital infection group 1500 cases. The small for gestational age infant, birth weight≤1500 g, gestational age≤37 weeks, amniotic fluid contamination, asphyxia neonatorum, parenteral alimentation, mechanical ventilation of two groups were detected, the high risk factors of hospital infection in NICU were analyzed by Logistic regression analysis. Results The differences of birth weight≤1500 g, gestational age≤37 weeks, asphyxia neonatorum, parenteral alimentation, mechanical ventilation between two groups were statistical significance (all P < 0.05), the Logistic regression analysis showed that, birth weight≤1500 g, gestational age≤37 weeks, asphyxia neonatorum, parenteral alimentation, mechanical ventilation were high risk factors of hospital infection in NICU (OR=1.818, 4.468, 4.049, 4.897, 3.768, all P < 0.05). Conclusion Avoiding high risk factors of hospital infection in NICU timely is an important meaning for prevention of hospital infection in NICU.
[Key words] NICU;Hospital infection;High risk factors
新生儿重症监护病房是收治早产儿、极低体重儿、呼吸窘迫综合征患儿的科室,患儿往往病情急、进展迅速,在进行侵入性操作时,医院感染的风险性明显增高[1-2]。医院感染一旦出现会加重新生儿的病情,延长住院时间和增加经济负担,影响患儿的预后水平[3-4]。针对新生儿重症监护病房医院临床资料进行分析,探讨影响新生儿重症监护病房医院感染的高危因素,对于积极采取预防措施,提高患儿预后具有重要的意义。本研究通过对滨州医学院烟台附属医院(以下简称“我院”)新生儿重症监护病房医院感染情况进行分析,现将结果报道如下:
1 资料与方法
1.1 一般资料
选取我院2013年5月~2014年8月新生儿重症监护室收治的病例1650例,依据是否发生医院感染进行临床分组,医院感染组150例,住院时间大于48 h,日龄小于28 d,符合医院感染诊断标准并确诊。……
