李艳艳+++邝平

[摘要] 目的 探讨盐酸奥洛他定滴眼液联合普拉洛芬滴眼液治疗儿童变态反应性结膜炎的临床效果。 方法 选取60例儿童变态反应性结膜炎患者，按照就诊顺序编号将其随机分为研究组与对照组，每组30例，对照组行普拉洛芬滴眼液治疗，研究组在对照组的基础上行盐酸奥洛他定滴眼液治疗，比较两组的治疗效果。 结果 治疗后研究组症状与体征评分明显低于对照组，差异有统计学意义（P<0.05）。对照组总有效率为40.0%，研究组总有效率为80.0%，研究组治疗效果明显优于对照组，差异有统计学意义（P<0.05）。 结论 盐酸奥洛他定滴眼液治疗儿童变态反应性结膜炎效果显著，安全性高，值得临床推广应用。

[关键词] 儿童变态反应性结膜炎；盐酸奥洛他定滴眼液；普拉洛芬滴眼液

[中图分类号] R777.31[文献标识码] A[文章编号] 1674-4721（2014）06（c）-0085-03

Clinical effect observation of olopatadine hydrochloride eye drops combined with pranoprofen drops in treatment of allergic conjunctivitis in children

LI Yan-yan1 KUANG Ping2

1.Department of Ophthalmology,Children′s Hospital in Jiangxi Province,Nanchang 330006,China;2.ENT of Shangli People′s Hospital in Pingxiang City of Jiangxi Province,Shangli 337009,China

[Abstract] Objective To investigate the clinical curative effect of olopatadine hydrochloride eye drops combined with pranoprofen drops in treatment of allergic conjunctivitis in children. Methods 60 cases of children with allergic conjunctivitis were selected,and were randomly divided into study group and control group according to the treatment of patients sequentially number,the control group were treated with eye drops pranoprofen drops,the study group were treated with olopatadine hydrochloride eye drops on the basis of control group,the clinical effect was compared. Results The signs and symptoms score of study group was lower than that of the control group,the difference was significant (P<05).The total effective rate of the control group was 40.0%,of the study group was 80.0%,the total effective rate of study group was better than that of the control group,the difference was significant (P<0.05). Conclusion The effect of olopatadine hydrochloride eye drops treating allergic conjunctivitis in children is well,is safe,be worthy of clinical application.

[Key words] Allergic conjunctivitis in children;Olopatadine hydrochloride eye drops;Pranoprofen drops

变态反应性结膜炎是一种临床上十分常见的过敏性眼部疾病，发病率较高，近20%的人伴有变态反应性结膜炎病症[1]，儿童群体尤其高发。随着现代化社会的发展，空气污染指数不断升高，其发病率逐年上升，对儿童患者生活与学习负面影响极大。现阶段，变态反应性结膜炎临床上多行抗过敏药物治疗，临床上常用的抗过敏药物种类多样，疗效不一。本文探讨盐酸奥洛他定滴眼液联合普拉洛芬滴眼液治疗儿童变态反应性结膜炎的临床效果。

1 资料与方法

1.1 一般资料

选取2012年3月～2014年3月本院收治的60例儿童变态反应性结膜炎患者，均符合《眼科全书》临床诊断标准[2]，排除其他角结膜炎患者及眼病史患者等。按照患儿就诊顺序编号将其随机分为研究组与对照组，每组30例，研究组男性17例，女性13例，年龄4～13岁，平均（8.5±2.0）岁；对照组男性16例，女性14例，年龄4～14岁，平均（9.0±1.8）岁；……