艾秀清　贾志莺　木妮热·木沙江

【摘要】 目的：探讨多普勒超声在乳腺癌术后锁骨区淋巴结节转移放射治疗临床疗效评价中的应用价值。方法：选取乳腺癌根治术后锁骨区淋巴结转移的30例患者行放射治疗，分别于治疗前、治疗后行彩色多普勒超声检查，就结果进行对比分析。结果：经放射治疗后，锁骨区转移淋巴结例数、数量均明显减少，二维超声大小、收缩期峰值流速、动脉频谱阻力指数均明显降低，差异均有统计学意义（P<0.05）。结论：彩色多普勒超声通过对乳腺癌术后转移淋巴结监测，能准确判断后续放射治疗的疗效，具有较大的临床应用价值。

【关键词】 彩色多普勒超声； 乳腺癌； 淋巴结转移； 放射治疗

【Abstract】 Objective：To investigate the clinical application of doppler ultrasound in breast cancer lymph node metastasis supraclavicular radiation in the clinical curative effect evaluation.Method：30 patients with mastectomy supraclavicular lymph node metastasis were selected and given radiation therapy.The results were compared before and after underwent color doppler ultrasound examination.Result：After radiation therapy，the number of cases of supraclavicular lymph nodes were significant reduced，the number of the size of the two-dimensional ultrasound，peak systolic velocity，arterial resistance index were significantly lower，the differences were statistically significant（P<0.05）.Conclusion：Color doppler ultrasound for breast cancer lymph node metastasis through monitoring，can accurately determine the efficacy of subsequent radiation therapy，with great clinical value.

【Key words】 Color doppler ultrasound； Breast cancer； Metastasis lymph nodes； Radiation therapy

First-authors address：The Affiliated Tumor Hospital of Xinjiang Medical University，Urumqi 830011，China

doi：10.3969/j.issn.1674-4985.2014.18.022

乳腺癌是严重威胁女性健康的恶性肿瘤，手术是常见的也是最有效的治疗方法。浸润和转移是恶性肿瘤的重要特征，淋巴结转移的程度是患者愈后的重要因素。局部放射治疗，抑制复发与转移是提高患者生存率与生存质量的关键，正确诊断锁骨区淋巴结有无转移对乳腺癌患者治疗和预后意义重大[1]。乳腺癌术后胸壁和/或区域淋巴结转移复发率在10%～20%，淋巴结数目越多，其复发转移率越高，5年、10年的生存率就越低，而锁骨区淋巴结转移的监测尤为重要[2]。

通过相关影像学检查对乳腺癌术后锁骨区淋巴结消除、转移情况进行观察是放射治疗疗效评价、后续治疗选择的重要依据[3]。本研究拟采用在彩色多普勒超声考虑乳腺癌术后锁骨区淋巴结肿大为转移时通过粗针穿刺活检进行病理证实。使用三维调强放疗对锁骨区淋巴结转移进行治疗，在放疗前、中……