许鸣 薛晏 叶淑  王家薇 李久海

[摘要] 目的 探讨GPH基因技术在治疗非淋等泌尿生殖感染中的临床效果。 方法 选择2012年8月~ 2013年10月哈尔滨市223例性病就诊者进行治疗，其中非淋菌性尿道炎91例，淋病64例,尖锐湿疣38列，生殖器疱疹，24例，软下疳6例，均有非婚性接触史。 结果 经过长达4～6个月的跟踪随访，治愈率为98.21%。 结论 GPH基因技术在治疗非淋等泌尿生殖感染方面取得了显著效果，充分显示出GPH基因技术所具有的疗效显著、治疗安全、不易复发的突出优势。

[关键词] GPH基因技术；治疗；非淋菌性尿道炎；泌尿生殖感染

[中图分类号] R446   [文献标识码] B   [文章编号] 2095-0616（2014）08-144-03

An analysis of the application of GPH gene technology in the treatment of urogenital infections such as non-gonococcal urethritis

XU Ming1  XUE Yan2  YE Shufen1  WANG Jiawei2  LI Jiuhai2

1.Harbin Centre for Disease Control and Prevention,Harbin 150056,China;2.Heilongjiang Service Centre for Reproductive Care,Harbin 150020,China

[Abstract] Objective To explore the clinical effect of GPH gene technology in the treatment of urogenital infections such as non-gonococcal urethritis. Methods 223 patients with sexually transmitted diseases who were treated in Harbin from August 2012 to October 2013 were selected, among whom 91 patients were diagnosed as non-gonococcal urethritis,64 gonorrhea,38 condyloma acuminatum,24 genital herpes and 6 chancroid.They all had unmarried sexual contact. ResultsThe recovery rate was 98.21% during follow-ups up to 4-6 months. Conclusion The GPH gene technology achieves significant effect in the treatment of urogenital infections such as non-gonococcal urethritis,which proves its outstanding advantages of significant curative effect,safe treatment and being uneasy to relapse.

[Key words] GPH gene technology;Treatment;Non-gonococcal urethritis;Urogenital infections

性传播疾病是以性接触为主要传播方式，危害人类最严重、发病最广泛的一组传染病，导致性病感染的病原微生物有许多种[1]，包括淋球菌、衣原体、支原体、人类乳头瘤病毒、梅毒螺旋体等感染引起的淋病、非淋菌性尿道炎、尖锐湿疣、生殖器疱疹、梅毒等，已经成为目前临床上最为多见的生殖感染疾病。性关系混乱是传播性病最主要和最直接的原因，卖淫嫖娼、性乱、婚前和婚外性行为、同性恋等非婚姻的性行为越普遍，性病的流行也越严重，不仅严重影响正常夫妻生活、破坏和谐的家庭关系、严重者更会危及生命，给患者及家庭带来巨大的经济和精神损失[2]，同时还严重危害社会。为了解决生殖感染疾病的彻底治疗问题，我们率先引进了GPH基因技术和法国梅里埃基因芯片病毒检测技术，开展治疗性研究，取得了一些经验，现报道如下。……