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99Tcm4O—SPECT显像在亚急性甲状腺炎中的诊断价值

2014-06-28范贤东庞华

中国医药科学 2014年4期

范贤东??庞华

[摘要] 目的 探讨99Tcm4O-SPECT显像在亚急性甲状腺炎中的诊断价值。方法 回顾性分析我院2011年5月~2013年5月收治的25例亚急性甲状腺炎患者的临床资料。结果 观察组和对照组患者的T/N值分别为(2.18±0.56)和(6.34±0.88),观察组患者的T/N值明显比对照组低,两者差异具有统计学意义(P<0.05);观察组患者的FT3、TMAb比对照组低,FT4、TSH、TGAb比对照组高,但是相比差异不具有统计学意义(P>0.05)。结论 亚急性甲状腺炎具有不断变化的病理过程,核素现象在其发病过程中有其特异性,对其诊断具有不可替代的作用。

[关键词] 99Tcm4O-SPECT显像;亚急性甲状腺炎;诊断价值

[中图分类号] R445.5 [文献标识码] B [文章编号] 2095-0616(2014)04-124-03

Value of 99Tcm4O-SPECT imaging in the diagnosis of subacute thyroiditis

FAN Xiandong PANG Hua

Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China

[Abstract] Objective To investigate the value of 99Tcm4O-SPECT imaging in the diagnosis of subacute thyroiditis. Methods The clinical data of 25 cases of subacute thyroiditis patients who had been treated in our hospital from May 2011 to May 2013 were retrospectively analyzed. Results The T / N ratio of observation group and control group patients were (2.18±0.56) and (6.34±0.88), the T / N ratio of patients in the observation group was significantly lower than that of the control group, the difference was statistically significant(P<0.05); the level of FT3, TMAb of patients in the observation group were lower, and FT4, TSH, TGAb higher than that of patients in the control group, but the differences were not statistically significant(P>0.05). Conclusion Subacute thyroiditis has changing pathological process, radionuclide phenomenon has its specially pathogenesis specificity and plays an irreplaceable role in its diagnosis.

[Key words] 99Tcm4O-SPECT imaging; Subacute thyroiditis; Value

本研究对我院近两年来收治的25例亚急性甲状腺炎患者的临床资料进行了回顾性分析,探讨了99Tcm4O-SPECT显像在亚急性甲状腺炎中的诊断价值,现报道如下。

1 资料与方法

1.1 一般资料

选取我院2011年5月~2013年5月收治的25例亚急性甲状腺炎患者,所有患者均有甲状腺肿大、质中等或稍硬等临床表现。其中男10例,女15例,年龄在21~52岁,平均(35.6±10.4)岁;病程4~36d,平均(15.5±10.2)d。经病理学细针穿刺检查,有17例患者为亚急性肉芽肿性甲状腺炎,8例患者为亚急性淋巴细胞性甲状腺炎。将这些患者作

为观察组,另选取同期来我院进行健康体检的人员25例作为对照组,所有人员均没有内分泌系统疾病,甲状腺静态现象显示均具有清晰的甲状腺显影和均匀的放射性分布(图1、2)。其中有男12例,女13例,年龄在21~50岁,平均为(32.3±10.6)岁。两组一般资料各方面的差异均无统计学意义(P>0.05),具有可比性。

1.2 方法

(1)血清放射免疫检查:让所有选取的受检者清晨空腹,对其周静脉血进行抽取,然后对血清进行分离,最后对血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、血清促甲状腺素(TSH)、甲状腺球蛋白抗体(TGAb)、甲状腺微粒体抗体(TMAb)进行测定;……

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