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奥曲肽联合中药治疗轻型急性胰腺炎的疗效观察

2014-01-13张勇

中国医学创新 2014年1期

张勇

【摘要】 目的:探讨奥曲肽联合中药治疗轻型急性胰腺炎的临床效果。方法:选取2010年3月-2012年3月本院收治的68例轻型急性胰腺炎患者,按随机数字表法分为观察组与对照组,每组各34例,对照组患者给予奥曲肽治疗,观察组患者在奥曲肽治疗的基础上联合中药大黄50 g治疗,两组患者均连续治疗7 d,观察临床治疗效果,记录患者临床症状消失时间、首次通便时间、血淀粉酶恢复正常时间及平均住院时间。结果:观察组治疗有效率为97.0%,对照组为82.4%,两组比较差异有统计学意义(P<0.05);观察组临床症状消失时间、首次通便时间、血淀粉酶恢复正常时间、平均住院时间均短于对照组,两组上述指标比较差异有统计学意义(P<0.05)。结论:采用奥曲肽联合中药治疗轻型急性胰腺炎临床效果显著,值得推广。

【关键词】 奥曲肽; 中药治疗; 轻型急性胰腺炎; 临床治疗效果

Treatment Efficacy of Octreotide Medicine on Mild Acute Pancreatitis/ZHANG Yong.//Medical Innovation of China,2014,11(01):114-116

【Abstract】 Objective:To explore clinical effect of octreotide medicine treatment on mild acute pancreatitis.Method:68 cases with mild acute pancreatitis in our hospital from March 2010 to March 2012 were selected and randomly divided into observation group and control group according to random number table method, each group had 34 patients, the control group was treated with octreotide, the observation group was treated with rhubarb 50 g on the basis of octreotide therapy, after 7 days of treatment, observed clinical treatment, recorded the clinical symptoms time, first purge time, serum amylase returned to normal and average length of stay.Result:The effective rate of the observation group was 97.0%, the control group was 82.4%, the difference of the two groups had statistical significance (P<0.05); time of clinical symptoms in patients, the first purge time, recovery time of serum amylase and average length of stay of the observation group were significantly shorter than the control group, these indicators of the two groups had statistical significance (P<0.05).Conclusion:Herbal treatment using octreotide mild acute pancreatitis significant clinical effect, is worth promoting.

【Key words】 Octreotide; Herbal Treatment; Mild acute pancreatitis; Clinical effect

First-authors address:The Maternal and Child Health Care Hospital of Dingnan County,Dingnan 341900,China

doi:10.3969/j.issn.1674-4985.2014.01.054

急性胰腺炎是由胰管内压突增、胰管阻塞及胰腺血液供应不足等引起的急性炎症,患者伴随着压痛反跳痛、呕吐、腹胀等症状,病情突发且发展快,及时治疗能够显著提高治疗有效率。目前临床治疗多采用保守治疗办法,笔者为对奥曲肽联合中药治疗轻型急性胰腺炎的临床效果进行观察,选取本院收治的68例轻型急性胰腺炎患者进行分组研究,具体报告如下。

1 资料与方法

1.1 一般资料 选取2010年3月-2012年3月本院收治的68例轻型急性胰腺炎患者,男42例,女26例,年龄24~72岁,平均43.8岁,发病时间3~15 h;患者均伴随呕吐、腹胀等临床症状;患者入院后结合临床表现、基本生命体征观察、CT及胰腺影像学检查,确诊为急性胰腺炎;依照我国急性胰腺炎诊治指南(草案)对患者病情进行分级[1],均为轻型胰腺炎。将患者按随机数字表法分为观察组与对照组,每组各34例,其中观察组男20例,女14例,年龄24~69岁,平均41.7岁,发病时间5~15 h;……

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