兰娜

[摘要] 目的 分析探讨不同雾化吸入方式对COPD急性期的临床护理疗效。 方法 将120例笔者所在医院治疗的COPD患者随机分为对照组及观察组，对照组给予超声雾化吸入治疗，观察组给予氧驱动雾化吸入治疗。 结果 两组患者治疗前PaO2、PaCO2、SO2 3项指标比较差异均无统计学意义。治疗第3天时两组PaO2、SO2均出现显著的提升，观察组两项指标显著高于对照组，两组间比较差异有统计学意义（P＜0.05）；治疗第7、14天时观察组PaO2、SO2显著高于对照组，两组间比较差异有统计学意义（P＜0.05）；观察组在第7、14天的PaCO2显著低于对照组，两组间比较差异有统计学意义（P＜0.05）。对照组显效33例（55.0％），有效17例（28.3％），总有效率83.3％；观察组显效38例（63.3％），有效20例（33.3％），总有效率为96.7％，观察组显著高于对照组，两组总有效率比较差异有统计学意义（P＜0.05）。 结论 氧驱动雾化吸入与超声雾化相比较，能更好的改善COPD患者肺通气换气功能，提高COPD治疗的总有效率，应在临床推广使用。

[关键词] 慢性阻塞性肺疾病；雾化吸入

[中图分类号] R563???[文献标识码] B???[文章编号] 2095-0616（2012）15-

Efficacy analysis of the clinical care of the different aerosol inhalation on chronic obstructive pulmonary disease in acute phase

LAN?Na

Emergency Department,the Traditional Chinese Medical Hospital of Qinghai Province,Xining 810000,China

[Abstract] Objective To explore the clinical care efficacy of the different aerosol inhalation on patients with COPD in acute phase. Methods 120 patients with COPD in our hospital were randomly divided into control group and observation group.The control group was treated with ultrasound inhalation therapy, and the observation group were treated with oxygen-driven inhalation therapy. Results PaO2, PaCO2, SO2 of the two groups before treatment had no significant difference in treatment on day 3.PaO2 and SO2 of two groups were significantly improved, but the two indicators of the observation group was significantly higher (P＜0.05).The 7th and 14th days of treatment, PaO2 and SO2 of the observation group were significantly higher than that of the control group(P＜0.05). PaCO2 of observation group was significantly lower, and there were significant differences between the two groups (P＜0.05). In control group, 33 cases were significantly effective (55.0%), 17 cases were effective (28.3%), and the total effective rate was 83.3%.In observation group, 38 cases were significantly effective (63.3%), 20 cases were effective (33.3%), and total effective rate was 96.7%. The total effective rate of two group were significant difference(P＜0.05), and the observation group was significantly higher. Conclusion Compared with ultrasonic atomization, oxygen atomizing inhalation is better to improve the ventilation function of lung ventilation of patients with COPD, improve the treatment total efficiency of COPD, and should be used in clinical practice.

[Key words] Chronic obstructive pulmonary disease; Aerosol inhalation

慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）是一种呈进行性进展、不完全可逆，具有气流受限特征的肺部疾病。COPD与吸烟、空气污染、感染等因素有关，是呼吸系统多发病。COPD发病率、病死率呈逐年上升趋势。目前居全球死亡原因第4位及全部疾病经济负担排名第5位[1-2]。COPD高发于发展中国家，我国约有COPD患者2 500万，40岁以上人群患病率为8.2％。在COPD急性期（AECOPD）采用综合治疗缓解病情，是降低死亡率，延缓疾病进展的措施。笔者所在医院呼吸内科于2010年1月～2011年12月采用氧驱动盐酸氨溴索注射液雾化吸入治疗AECOPD患者60例，取得较好疗效，现报道如下。……